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Amination of a Green Solvent via Immobilized Biocatalysis for the Synthesis of Nemtabrutinib

Christopher K. Prier, Karla Camacho Soto, Jacob H. Forstater, Nadine Kuhl, Jeffrey T. Kuethe, Wai Ling Cheung-Lee, Michael J. Di Maso, Claire M. Eberle, Shane T. Grosser, Hsing-I Ho, Erik Hoyt, Anne Maguire, Kevin M. Maloney, Amanda Makarewicz, Jonathan P. McMullen, Jeffrey C. Moore, Grant S. Murphy, Karthik Narsimhan, Weilan Pan, Nelo R. Rivera, Anumita Saha-Shah, David A. Thaisrivongs, Deeptak Verma, Adeya Wyatt, Daniel Zewge

Version 1 posted 06 March 2023

491

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Biological and Medicinal Chemistry

Working Paper

Active site remodelling of a cyclodipeptide synthase redefines substrate scope

Emmajay Sutherland, Christopher Harding, Clarissa Czekster

Version 2 posted 08 March 2022

388

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Physical Chemistry

Working Paper

Feedback inhibition of DszC, a crucial enzyme for crude oil biodessulfurization

Rui Pedro Pimenta das Neves, Bruno Miguel Viveiros Araújo, Maria João Ramos, Pedro Alexandrino Fernandes

Version 1 posted 03 March 2023

90

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Catalysis

Review

Strategic Enzymatic Transformations in Modern Natural Product Synthesis

Felix Kaspar, Anett Schallmey

Version 1 posted 02 May 2022

495

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Catalysis

Working Paper

Directed Evolution of a Ketone Synthase for Efficient and Highly Selective Functionalization of Internal Alkenes by Accessing Reactive Carbocation Intermediates

Sebastian Gergel, Jordi Soler, Alina Klein, Kai Schülke, Bernhard Hauer, Marc Garcia-Borràs, Stephan Hammer

Version 1 posted 05 January 2022

1,197

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5

Citations

Biological and Medicinal Chemistry

Working Paper

Rational Engineering of Hydratase from Lactobacillus Acidophilus Reveals Critical Residues Directing Substrate Specificity and Regioselectivity

Bekir Engin Eser, Michal Poborsky, Rongrong Dai, Shigenobu Kishino, Anita Ljubic, Michiki Takeuchi, Charlotte Jacobsen, Jun Ogawa, Peter Kristensen, Zheng Guo

Version 2 posted 04 June 2019

947

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2

Citations

Catalysis

Working Paper

Bioinformatics-Guided Discovery of Citrulline 4-Hydroxylase from GE81112 Biosynthesis and Rational Engineering of Its Substrate Specificity

Christian Zwick, Max Sosa, Hans Renata

Version 1 posted 20 August 2019

522

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Catalysis

Working Paper

Engineering Protein Dynamics of Ancestral Luciferase

Andrea Schenkmayerova, Gaspar Pinto, Martin Toul, Martin Marek, Lenka Hernychova, Joan Planas-Iglesias, Veronika Liskova, Daniel Pluskal, Michal Vasina, Stephane Emond, Mark Doerr, Radka Chaloupková, David Bednar, Zbynek Prokop, Florian Hollfelder, Uwe T. Bornscheuer, Jiri Damborsky

Version 1 posted 17 August 2020

370

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1

Citations

Catalysis

Working Paper

Directed Evolution of an Feᴵᴵ-Dependent Halogenase for Asymmetric C(sp³)-H Chlorination

Sabine Duewel, Luca Schmermund, Tabea Faber, Klaus Harms, Vasundara Srinivasan, Eric Meggers, Sabrina Hoebenreich

Version 1 posted 05 November 2019

855

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Catalysis

Working Paper

A Designed Photoenzyme Promotes Enantioselective [2+2]-Cycloadditions via Triplet Energy Transfer

Jonathan S. Trimble, Rebecca Crawshaw, Florence J. Hardy, Colin W. Levy, Murray J.B. Brown, Douglas E. Fuerst, Derren Heyes, Richard Obexer, Anthony P. Green

Version 1 posted 13 May 2022

1,672

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18 results in enzyme engineering in Keywords: enzyme engineering

Amination of a Green Solvent via Immobilized Biocatalysis for the Synthesis of Nemtabrutinib

Active site remodelling of a cyclodipeptide synthase redefines substrate scope

Feedback inhibition of DszC, a crucial enzyme for crude oil biodessulfurization

Strategic Enzymatic Transformations in Modern Natural Product Synthesis

Directed Evolution of a Ketone Synthase for Efficient and Highly Selective Functionalization of Internal Alkenes by Accessing Reactive Carbocation Intermediates

Rational Engineering of Hydratase from Lactobacillus Acidophilus Reveals Critical Residues Directing Substrate Specificity and Regioselectivity

Bioinformatics-Guided Discovery of Citrulline 4-Hydroxylase from GE81112 Biosynthesis and Rational Engineering of Its Substrate Specificity

Engineering Protein Dynamics of Ancestral Luciferase

Directed Evolution of an Feᴵᴵ-Dependent Halogenase for Asymmetric C(sp³)-H Chlorination

A Designed Photoenzyme Promotes Enantioselective [2+2]-Cycloadditions via Triplet Energy Transfer

18 results in Keywords: enzyme engineering