Search

11 results in Keywords: Cytochrome P450

Structure and Function of NzeB, a Versatile C–C and C–N Bond Forming Diketopiperazine Dimerase

Vikram V. Shende, Yogan Khatri, Sean A. Newmister, Jacob N. Sanders, Petra Lindovska, Fengan Yu, Tyler J. Doyon, Justin Kim, Mohammad Movassaghi, Kendall N Houk, David H. Sherman

Version 1 posted 15 May 2020

745

Downloads

Catalysis

Working Paper

Engineering P450 TamI as an Iterative Biocatalyst for Selective Late-Stage C-H Functionalization and Epoxidation of Tirandamycin Antibiotics

Rosa V. Espinoza, Kersti Caddell Haatveit, S. Wald Grossman, Jin Yi Tan, Caylie A. McGlade, Yogan Khatri, Sean A. Newmister, Jennifer J. Schmidt, Marc Garcia-Borràs, John Montgomery, Kendall N Houk, David H. Sherman

Version 1 posted 16 March 2021

464

Downloads

Biological and Medicinal Chemistry

Working Paper

Molecular Basis of Iterative C–H Oxidation by TamI, a Multifunctional P450 Monooxygenase from the Tirandamycin Biosynthetic Pathway

Sean A. Newmister, Kinshuk Raj Srivastava, Rosa V. Espinoza, Kersti Caddell Haatveit, Yogan Khatri, Rachel M. Martini, Marc Garcia-Borràs, Larissa M. Podust, Kendall N Houk, David H. Sherman

Version 1 posted 27 July 2020

430

Downloads

Catalysis

Working Paper

Local Electric Fields Dictate Function: The Different Product Selectivity Observed for Fatty Acids Oxidation by Two Deceptively Very Similar P450-Peroxygenases OleT and BSbeta

Shalini Yadav, Sason Shaik, Shakir Ali Siddiqui, Surajit Kalita, Kshatresh Dubey

Version 1 posted 29 June 2021

408

Downloads

Biological and Medicinal Chemistry

Working Paper

Cryptic isomerization in diterpene biosynthesis and the restoration of an evolutionarily defunct P450

Zining Li, Baofu Xu, Tyler Alsup, Xiuting Wei, Wenbo Ning, Daniel Icenhour, Michelle Ehrenberger, Ion Ghiviriga, Bao-Doan Giang, Jeffrey Rudolf

Version 1 posted 30 August 2023

366

Downloads

Organic Chemistry

Working Paper

Epoxidation and late-stage C-H functionalization by P450 TamI is mediated by variant heme-iron oxidizing species

Rosa V. Espinoza, Mark A. Maskeri, Aneta Turlik, Anjanay Nangia, Yogan Khatri, John Montgomery, Ken N. Houk, David H. Sherman

Version 1 posted 14 September 2021

569

Downloads

Biological and Medicinal Chemistry

Working Paper

Cytochrome P450-Mediated Cyclization in Eunicellane-Derived Diterpenoid Biosynthesis

Zengyuan Wang, Qian Yang, Jingyi He, Haixin Li, Xingming Pan, Zining Li, Hui-Min Xu, Jeffrey D. Rudolf, Dean J. Tantillo, Liao-Bin Dong

Version 1 posted 09 March 2023

824

Downloads

Biological and Medicinal Chemistry

Working Paper

Insights into substrate recognition by the unusual nitrating enzyme RufO

Benjamin Dratch, Kirklin McWhorter, Tamra Blue, Stacey Jones, Samantha Horwitz, Katherine Davis

Version 1 posted 02 June 2023

225

Downloads

Catalysis

Working Paper

A Single Site Mutation Induces a Water-Mediated Promiscuity in Lignin Breaking Cytochrome P450GcoA

Warispreet Singh, Sonia Santos, Paul James, Gary Black, Meilan Huang, Kshatresh Dubey

Version 2 posted 08 April 2022

208

Downloads

Biological and Medicinal Chemistry

Working Paper

Structure, in Vivo Detection and Anti-Bacterial Activity of Metabolites of SQ109, an Anti-Infective Drug Candidate

Satish Malwal, Matthew D. Zimmerman, Nadine Alvarez, Jansy Sarathy, Veronique Dartois, Carol A. Nacy, Eric Oldfield

Version 1 posted 26 May 2021

370

Downloads

Search

Refine Search

11 results in Cytochrome P450 in Keywords: Cytochrome P450

Structure and Function of NzeB, a Versatile C–C and C–N Bond Forming Diketopiperazine Dimerase

Engineering P450 TamI as an Iterative Biocatalyst for Selective Late-Stage C-H Functionalization and Epoxidation of Tirandamycin Antibiotics

Molecular Basis of Iterative C–H Oxidation by TamI, a Multifunctional P450 Monooxygenase from the Tirandamycin Biosynthetic Pathway

Local Electric Fields Dictate Function: The Different Product Selectivity Observed for Fatty Acids Oxidation by Two Deceptively Very Similar P450-Peroxygenases OleT and BSbeta

Cryptic isomerization in diterpene biosynthesis and the restoration of an evolutionarily defunct P450

Epoxidation and late-stage C-H functionalization by P450 TamI is mediated by variant heme-iron oxidizing species

Cytochrome P450-Mediated Cyclization in Eunicellane-Derived Diterpenoid Biosynthesis

Insights into substrate recognition by the unusual nitrating enzyme RufO

A Single Site Mutation Induces a Water-Mediated Promiscuity in Lignin Breaking Cytochrome P450GcoA

Structure, in Vivo Detection and Anti-Bacterial Activity of Metabolites of SQ109, an Anti-Infective Drug Candidate

11 results in Keywords: Cytochrome P450