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Biological and Medicinal Chemistry

Working Paper

Computational Modeling of Conformer Stability in Benenodin-1, A Thermally-Actuated Lasso Peptide Switch

Zhongyue Yang, Natalia Hajlasz, Heather Kulik

Version 1 posted 01 February 2022

223

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Biological and Medicinal Chemistry

Working Paper

Heterologous Production of Lasso Peptide Capistruin in a Burkholderia Host

Sylvia Kunakom, Alessandra Eustaquio

Version 1 posted 29 October 2019

614

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Biological and Medicinal Chemistry

Working Paper

Exploring the Chemical Space of Antiparasitic Peptides and Discovery of New Promising Leads through a Novel Approach based on Network Science and Similarity Searching

Sebastián Ayala-Ruano, Yovani Marrero-Ponce, Longendri Aguilera‑Mendoza, Noel Pérez, Guillermin Agüero-Chapin, Agostinho Antunes, Ana Cristina Aguilar

Version 2 posted 11 February 2022

533

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Analytical Chemistry

Working Paper

Baldwin and Whitehead’s Manzamine Alkaloids Biosynthesis Hy-pothesis Involves a Finely Tuned Reactivity of C3 Unit: a High-Throughput Experimentation Approach

Axel Leblond, Alexandre Nguyen, Charlotte Alcover, Karine Leblanc, Jean-François Gallard, Delphine Joseph, Erwan Poupon, Mehdi Beniddir

Version 2 posted 17 January 2024

488

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1

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Organic Chemistry

Working Paper

Pseudo High-Throughput Development and Optimization of the Electrochemical Oxidation of Sensitive Propargylic Benzylic Alco-hols

Chad Hatch, Maxwell Martin, Danielle Beam, Glenn Yap, Matthew Von Bargen, Joel Rosenthal, William Chain

Version 1 posted 23 November 2021

282

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Organic Chemistry

Working Paper

Developing Photoaffinity Probes for Dopamine Receptor D2 to Determine Targets of Parkinson’s Disease Drugs

Spencer Kim, Emma Doukmak, Raymond Flax, Dylan Gray, Victoria Zirimu, Ebbing de Jong, Rachel Steinhardt

Version 1 posted 21 July 2022

324

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Organic Chemistry

Working Paper

Total Synthesis of Ginkgolide C and Formal Synthesis Ginkgolides A and B

Louis Barriault, Martin Hébert, Gabriel Bellavance

Version 1 posted 04 August 2022

1,033

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Theoretical and Computational Chemistry

Working Paper

Effectiveness of molecular fingerprints for exploring the chemical space of natural products

Davide Boldini, Davide Ballabio, Viviana Consonni, Roberto Todeschini, Francesca Grisoni, Stephan Sieber

Version 2 posted 21 December 2023

481

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Biological and Medicinal Chemistry

Working Paper

Reverse-Engineered High-Yield Lasso Peptide Production in an Alternative Host

Hannah Fernandez, Ashley Kretsch, Sylvia Kunakom, Adjo Kadjo, Douglas Mitchell, Alessandra Eustaquio

Version 1 posted 26 September 2023

158

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Biological and Medicinal Chemistry

Working Paper

Biomimetic Synthesis and Chemical Proteomics Reveal the Mechanism of Action and Functional Targets of Phloroglucinol Meroterpenoids

Amy Bracken, Colby Gekko, Nina Suss, Emma Lueders, Qi Cui, Qin Fu, Elizabeth Anderson, Sheng Zhang, Mikail Abbasov

Version 1 posted 29 September 2023

1,004

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Refine Search

13 results in lasso peptide, antibiotic , bioinformatics, natural products in Keywords: lasso peptide, antibiotic , bioinformatics, natural products

Computational Modeling of Conformer Stability in Benenodin-1, A Thermally-Actuated Lasso Peptide Switch

Heterologous Production of Lasso Peptide Capistruin in a Burkholderia Host

Exploring the Chemical Space of Antiparasitic Peptides and Discovery of New Promising Leads through a Novel Approach based on Network Science and Similarity Searching

Baldwin and Whitehead’s Manzamine Alkaloids Biosynthesis Hy-pothesis Involves a Finely Tuned Reactivity of C3 Unit: a High-Throughput Experimentation Approach

Pseudo High-Throughput Development and Optimization of the Electrochemical Oxidation of Sensitive Propargylic Benzylic Alco-hols

Developing Photoaffinity Probes for Dopamine Receptor D2 to Determine Targets of Parkinson’s Disease Drugs

Total Synthesis of Ginkgolide C and Formal Synthesis Ginkgolides A and B

Effectiveness of molecular fingerprints for exploring the chemical space of natural products

Reverse-Engineered High-Yield Lasso Peptide Production in an Alternative Host

Biomimetic Synthesis and Chemical Proteomics Reveal the Mechanism of Action and Functional Targets of Phloroglucinol Meroterpenoids

13 results in Keywords: lasso peptide, antibiotic , bioinformatics, natural products