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Biological and Medicinal Chemistry

Working Paper

Structural Characterization of Agonist Binding to A3 Adenosine Receptor through Biomolecular Simulations and Mutagenesis Experiments

Dimitrios Stamatis, Panagiotis Lagarias, Kerry Barkan, Eleni Vrontaki, Graham Ladds, Antonios Kolocouris

Version 1 posted 22 July 2019

614

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Biological and Medicinal Chemistry

Working Paper

Characterization of Protease-Activated Receptor (PAR) Ligands: Parmodulins Are Reversible Allosteric Inhibitors of PAR1-Driven Calcium Mobilization in Endothelial Cells

Disha M. Gandhi, Mark W. Majewski, Ricardo Rosas, Kaitlin Kentala, Trevor J. Foster, Eric Greve, Chris Dockendorff

Version 1 posted 21 February 2018

543

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Biological and Medicinal Chemistry

Working Paper

Improved GPCR Ligands Based on Genetically Impossible Nanobody-Peptide Fusions

Ross Cheloha, Fabian A. Fischer, Andrew W. Woodham, Eileen Daley, Naomi Suminski, Thomas J. Gardella, Hidde L. Ploegh

Version 1 posted 15 August 2019

653

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Biological and Medicinal Chemistry

Working Paper

BiasNet: A model to predict ligand bias towards GPCR signaling

Jason Sanchez, Govinda KC, Julian Franco, Jesus Garcia, suman sirimulla

Version 2 posted 18 March 2021

797

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Organic Chemistry

Working Paper

Optical Control of Cannabinoid Receptor 2–Mediated Ca2+ Release Enabled By Synthesis of Photoswitchable Probes

Roman Sarott, Alexander E.G. Viray, Patrick Pfaff, Anastasiia Sadybekov, Gabriela Rajic, Vsevolod Katritch, Erick Carreira, James Frank

Version 1 posted 28 July 2020

824

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Organic Chemistry

Working Paper

Platform Reagents Enable Synthesis of Ligand-Directed Cova-lent Probes: Study of Cannabinoid Receptor 2 in Live Cells

Erick Carreira, Miroslav Kosar, David Sykes, Alexander Viray, Rosa Maria Vitale, Roman Sarott, Rudolf Ganzoni, David Onion, Janelle Tobias, Philipp Leippe, Christoph Ullmer, Elisabeth Zirwes, Wolfgang Guba, Uwe Grether, James Frank, Dmitry Veprintsev

Version 1 posted 23 December 2022

467

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Biological and Medicinal Chemistry

Working Paper

Nile Red-Based GPCR Ligands as Ultrasensitive Probes of the Local Lipid Microenvironment of the Receptor

Fabien Hanser, Claire Marsol, Christel Valencia, Pascal Villa, Andrey S. Klymchenko, Dominique Bonnet, Iuliia Karpenko

Version 1 posted 18 November 2020

806

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Biological and Medicinal Chemistry

Working Paper

Discovery of 2-aminopyrimidines as potent agonists for the bitter taste receptor TAS2R14

Lukas Waterloo, Tara Pfeiffer, Harald Huebner, Fabrizio Fierro, Regine Brox, Stefan Löber, Dorothee Weikert, Masha Y. Niv, Peter Gmeiner

Version 1 posted 24 November 2022

320

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Biological and Medicinal Chemistry

Working Paper

A fluorescent photoaffinity probe for formyl peptide receptor 1 labelling in living cells

Devon Field, Stuart Warriner, Megan Wright

Version 1 posted 09 September 2022

198

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Theoretical and Computational Chemistry

Working Paper

3DDPDs: Describing protein dynamics for proteochemometric bioactivity prediction. A case for (mutant) G protein-coupled receptors

Marina Gorostiola González, Remco L. van den Broek, Thomas G.M. Braun, Magdalini Chatzopoulou, Willem Jespers, Adriaan P. IJzerman, Laura H. Heitman, Gerard J.P. van Westen

Version 1 posted 23 May 2023

141

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17 results in GPCR in Keywords: GPCR

Structural Characterization of Agonist Binding to A3 Adenosine Receptor through Biomolecular Simulations and Mutagenesis Experiments

Characterization of Protease-Activated Receptor (PAR) Ligands: Parmodulins Are Reversible Allosteric Inhibitors of PAR1-Driven Calcium Mobilization in Endothelial Cells

Improved GPCR Ligands Based on Genetically Impossible Nanobody-Peptide Fusions

BiasNet: A model to predict ligand bias towards GPCR signaling

Optical Control of Cannabinoid Receptor 2–Mediated Ca2+ Release Enabled By Synthesis of Photoswitchable Probes

Platform Reagents Enable Synthesis of Ligand-Directed Cova-lent Probes: Study of Cannabinoid Receptor 2 in Live Cells

Nile Red-Based GPCR Ligands as Ultrasensitive Probes of the Local Lipid Microenvironment of the Receptor

Discovery of 2-aminopyrimidines as potent agonists for the bitter taste receptor TAS2R14

A fluorescent photoaffinity probe for formyl peptide receptor 1 labelling in living cells

3DDPDs: Describing protein dynamics for proteochemometric bioactivity prediction. A case for (mutant) G protein-coupled receptors

17 results in Keywords: GPCR