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Optical Control of Cannabinoid Receptor 2–Mediated Ca2+ Release Enabled By Synthesis of Photoswitchable Probes

Roman Sarott, Alexander E.G. Viray, Patrick Pfaff, Anastasiia Sadybekov, Gabriela Rajic, Vsevolod Katritch, Erick Carreira, James Frank

Version 1 posted 28 July 2020

884

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Biological and Medicinal Chemistry

Working Paper

Structural Characterization of Agonist Binding to A3 Adenosine Receptor through Biomolecular Simulations and Mutagenesis Experiments

Dimitrios Stamatis, Panagiotis Lagarias, Kerry Barkan, Eleni Vrontaki, Graham Ladds, Antonios Kolocouris

Version 1 posted 22 July 2019

642

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Biological and Medicinal Chemistry

Working Paper

Characterization of Protease-Activated Receptor (PAR) Ligands: Parmodulins Are Reversible Allosteric Inhibitors of PAR1-Driven Calcium Mobilization in Endothelial Cells

Disha M. Gandhi, Mark W. Majewski, Ricardo Rosas, Kaitlin Kentala, Trevor J. Foster, Eric Greve, Chris Dockendorff

Version 1 posted 21 February 2018

560

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Biological and Medicinal Chemistry

Working Paper

Improved GPCR Ligands Based on Genetically Impossible Nanobody-Peptide Fusions

Ross Cheloha, Fabian A. Fischer, Andrew W. Woodham, Eileen Daley, Naomi Suminski, Thomas J. Gardella, Hidde L. Ploegh

Version 1 posted 15 August 2019

698

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Biological and Medicinal Chemistry

Working Paper

BiasNet: A model to predict ligand bias towards GPCR signaling

Jason Sanchez, Govinda KC, Julian Franco, Jesus Garcia, suman sirimulla

Version 2 posted 18 March 2021

851

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Theoretical and Computational Chemistry

Working Paper

Challenges of Absolute Binding Free Energies for Membrane Exposed Binding Pockets

Charlie Cook, Irfan Alibay, Nithishwer Anand Mouroug, Ewa Chudyk, Ron Knegtel, Philip Biggin

Version 1 posted 13 August 2024

246

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Biological and Medicinal Chemistry

Working Paper

A modular click ligand-directed approach to label endogenous aminergic GPCRs in live cells

Xavier Gómez-Santacana, Marin Boutonnet, Carles Martínez-Juvés, Juan Lorenzo Catena, Enora Moutin, Thomas Roux, Eric Trinquet, Laurent Lamarque, Julie Perroy, Laurent Prézeau, Jurriaan M. Zwier, Jean-Philippe Pin, Amadeu Llebaria

Version 2 posted 20 September 2022

585

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1

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Biological and Medicinal Chemistry

Working Paper

Crystal Structure Reveals the Binding Mode and Selectivity of a Photoswitchable Ligand for the Adenosine A2A Receptor

Tsuyoshi Araya, Yuya Matsuba, Harufumi Suzuki, Tomohiro Doura, Nipawan Nuemket, Eriko Nango, Masaki Yamamoto, Dohyun Im, Hidetsugu Asada, Shigeki Kiyonaka, So Iwata

Version 1 posted 25 October 2023

276

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Organic Chemistry

Working Paper

Decoding the Molecular Dance: In Silico Exploration of Cannabinoid Interactions with Key Protein Targets for Therapeutic Insights

Maite Docampo-Palcios, Giovanni Ramirez, Tesfay Tesfatsion, Monica Pittiglio, Kyle Ray, Westley Cruces

Version 2 posted 10 January 2024

514

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Biological and Medicinal Chemistry

Working Paper

Proximity-assisted screening of class A/B hybrid GPCRs

Monika Gnatzy, Steffen Hartmann, Felix Hausch

Version 1 posted 01 July 2024

101

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19 results in GPCR in Keywords: GPCR

Optical Control of Cannabinoid Receptor 2–Mediated Ca2+ Release Enabled By Synthesis of Photoswitchable Probes

Structural Characterization of Agonist Binding to A3 Adenosine Receptor through Biomolecular Simulations and Mutagenesis Experiments

Characterization of Protease-Activated Receptor (PAR) Ligands: Parmodulins Are Reversible Allosteric Inhibitors of PAR1-Driven Calcium Mobilization in Endothelial Cells

Improved GPCR Ligands Based on Genetically Impossible Nanobody-Peptide Fusions

BiasNet: A model to predict ligand bias towards GPCR signaling

Challenges of Absolute Binding Free Energies for Membrane Exposed Binding Pockets

A modular click ligand-directed approach to label endogenous aminergic GPCRs in live cells

Crystal Structure Reveals the Binding Mode and Selectivity of a Photoswitchable Ligand for the Adenosine A2A Receptor

Decoding the Molecular Dance: In Silico Exploration of Cannabinoid Interactions with Key Protein Targets for Therapeutic Insights

Proximity-assisted screening of class A/B hybrid GPCRs

19 results in Keywords: GPCR