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The Mce3R stress-resistance pathway is vulnerable to small-molecule targeting that improves tuberculosis drug activities

Xinxin Yang, Tianao Yuan, Rui Ma, Kieran Chacko, Melissa Smith, Gintaras Deikus, Robert Sebra, Andrew Kasarskis, Harm van Bakel, Scott G. Franzblau, Nicole Sampson

Version 3 posted 28 March 2019

1,252

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Organic Chemistry

Working Paper

Diastereoselectivity is in the Details: Minor Changes Yield Major Improvements to the Synthesis of Bedaquiline

Sarah Mear, Tobias Lucas, Grace Ahlqvist, Juliana Robey, Jule-Philipp Dietz, Pankaj Khairnar, Sanjay Maity, Corshai Williams, David Snead, Ryan Nelson, Till Opatz, Timothy Jamison

Version 1 posted 31 March 2022

520

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Organic Chemistry

Working Paper

Development of a Practical Synthesis of the 8-FDC Fragment of OPC-167832

Vijayagopal Gopalsamuthiram, Dang Ho, Cheryl Peck, Vasudevan Natarajan, Toolika Agrawal, Justina Burns, John Blachert, Daniel Cook, Rodger Stringham, Ryan Nelson, Saeed Ahmad, Frank Gupton, David Snead, Tyler McQuade, Rajappa Vaidyanathan, Kai Donsbach, Joshua Sieber

Version 1 posted 26 November 2021

259

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Biological and Medicinal Chemistry

Working Paper

Molecular Dynamics of Mycolic Acid Monolayers

Wilma Groenewald, Monica Bulacu, Anna Croft, Siewert-Jan Marrink

Version 1 posted 27 March 2019

659

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2

Citations

Biological and Medicinal Chemistry

Working Paper

Data for Molecular Dynamics Simulations of Escherichia Coli Cytochrome Bd Oxidase with the Amber Force Field

Surl-Hee Ahn, Christian Seitz, Vinicius Cruzeiro, James McCammon, Andreas Goetz

Version 1 posted 28 April 2021

462

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Theoretical and Computational Chemistry

Working Paper

Structural and Functional Annotation of Uncharacterized Protein NCGM946K2_146 of Mycobacterium tuberculosis: An In-Silico Approach

Abu Saim Mohammad Saikat

Version 1 posted 28 August 2020

254

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Biological and Medicinal Chemistry

Working Paper

The myxobacterial antibiotic myxovalargin: Biosynthesis, structural revision, total synthesis and molecular characterization of ribosomal inhibition

Timm O. Koller, Ullrich Scheid, Teresa Kösel, Jennifer Herrmann, Daniel Krug, Helena I. Boshoff, Bertrand Beckert, Joanna C. Evans, Jan Schlemmer, Becky Sloan, Danielle M. Weiner, Laura E. Via, Atica Moosa, Thomas R. Ioerger, Franziska Gille, Maik Siebke, Tim Seedorf, Oliver Plettenburg, Anna-Luisa Warnke, Joachim Ullrich, Ralf Warrass, Clifton E. Barry, Digby F. Warner, Valerie Mizrahi, Andreas Kirschning, Daniel N. Wilson, Rolf Müller

Version 1 posted 21 July 2022

442

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Nanoscience

Review

The multivalency game ruling the biology of immunity

Lara Victoria Aiassa, Giuseppe Battaglia, Loris Rizzello

Version 1 posted 07 July 2023

132

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Theoretical and Computational Chemistry

Working Paper

Assessing the Stability of Isoniazid(INH) and Phenol Hydrazide Synthons in Tuberculosis Drugs: A Comparative Study via Benzaldehyde-Derived Phenolic Hydrazone Formation

Natalie Yeung

Version 1 posted 17 October 2023

99

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Biological and Medicinal Chemistry

Working Paper

Pathogen-Specific De Novo Antimicrobials Engineered Through Membrane Porin Biomimicry

Andrew Simonson, Agustey Mongia, Matthew R. Aronson, John N. Alumasa, Dennis Chan, Adam Bolotsky, Aida Ebrahimi, Elizabeth A. Proctor, Kenneth C. Keiler, Scott Medina

Version 1 posted 12 May 2020

525

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2

Citations

Refine Search

16 results in tuberculosis in Keywords: tuberculosis

The Mce3R stress-resistance pathway is vulnerable to small-molecule targeting that improves tuberculosis drug activities

Diastereoselectivity is in the Details: Minor Changes Yield Major Improvements to the Synthesis of Bedaquiline

Development of a Practical Synthesis of the 8-FDC Fragment of OPC-167832

Molecular Dynamics of Mycolic Acid Monolayers

Data for Molecular Dynamics Simulations of Escherichia Coli Cytochrome Bd Oxidase with the Amber Force Field

Structural and Functional Annotation of Uncharacterized Protein NCGM946K2_146 of Mycobacterium tuberculosis: An In-Silico Approach

The myxobacterial antibiotic myxovalargin: Biosynthesis, structural revision, total synthesis and molecular characterization of ribosomal inhibition

The multivalency game ruling the biology of immunity

Assessing the Stability of Isoniazid(INH) and Phenol Hydrazide Synthons in Tuberculosis Drugs: A Comparative Study via Benzaldehyde-Derived Phenolic Hydrazone Formation

Pathogen-Specific De Novo Antimicrobials Engineered Through Membrane Porin Biomimicry

16 results in Keywords: tuberculosis