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Biological and Medicinal Chemistry

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Organic Chemistry

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bromodomains

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4 results in Keywords: bromodomains

Biological and Medicinal Chemistry

Covalent-Fragment Screening of Brd4 Identifies a Ligandable Site Orthogonal to the Acetyl-Lysine Binding Sites

Michael Olp, Daniel Sprague, Stefan Kathman, Ziyang Xu, Alexandar Statsyuk, Brian Smith

Version 1 posted 12 July 2019

950

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Organic Chemistry

Stereoselective Synthesis of Allele-Specific BET Inhibitors

Adam Bond, Andrea Testa, Alessio Ciulli

Version 1 posted 18 May 2020

576

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Biological and Medicinal Chemistry

Identification of histone peptide binding specificity and small molecule ligands for the bromodomains of TRIM33α and TRIM33β

Angelina Sekirnik, Jessica Reynolds, Larissa See, Joseph Bluck, Amy Scorah, Cynthia Tallant, Bernadette Lee, Katarzyna Leszczynska, Rachel Grimley, Ian Storer, Marta Malattia, Sara Crespillo, Sofia Caria, Stephanie Duclos, Ester Hammond, Stefan Knapp, Garrett Morris, Fernanda Duarte, Philip Biggin, Stuart Conway

Version 1 posted 29 March 2022

448

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Biological and Medicinal Chemistry

Mutate and Conjugate: A Method to Enable Rapid In-Cell Target Validation

Adam Thomas, Marta Serafini, Emma Grant, Edward Coombs, Joseph Bluck, Matthias Schiedel, Michael McDonough, Jessica Reynolds, Bernadette Lee, Michael Platt, Vassilena Sharlandjieva, Philip Biggin, Fernanda Duarte, Thomas Milne, Jacob Bush, Stuart Conway

Version 1 posted 25 July 2023

378

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