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Biological and Medicinal Chemistry

Working Paper

Synthesis and Biological Evaluation of Iodinated Fidaxomicin Antibiotics

Andrea Dorst, Inga S. Shchelik, Daniel Schäfle, Peter Sander, Karl Gademann

Version 2 posted 21 July 2020

562

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Biological and Medicinal Chemistry

Working Paper

An Experimental Toolbox for Structure-Based Hit Discovery for P. Aeruginosa FabF, a Promising Target for Antibiotics

Ludvik Olai Espeland, Charis Georgiou, Raphael Klein, Hemalatha Bhukya, Bengt Erik Haug, Jarl Underhaug, Prathama S. Mainkar, Ruth Brenk

Version 1 posted 03 May 2021

336

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Biological and Medicinal Chemistry

Working Paper

Synthetic Studies with the Brevicidine and Laterocidine Lipopeptide Antibiotics Including Analogues with Enhanced Properties and in vivo Efficacy

Karol Al-Ayed, Ross D. Ballantine, Michael Hoekstra, Samantha Bann, Charlotte Wesseling, Alexander Bakker, Zheng Zhong, Yongxin Li, Mario van der Stelt, Stephen Cochrane, Nathaniel Martin

Version 2 posted 10 January 2022

1,202

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Organic Chemistry

Working Paper

A Practical, Component-Based Synthetic Route to Methylthiolincosamine Permitting Facile Northern-Half Diversification of Lincosamide Antibiotics

Matthew Mitcheltree, Jack W. Stevenson, Amarnath Pisipati, Andrew G. Myers

Version 1 posted 30 March 2021

365

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Organic Chemistry

Working Paper

Synthesis and Biological Evaluation of the Antimicrobial Natural Product Lipoxazolidinone A

Jonathan J. Mills, Kaylib R. Robinson, Troy E. Zehnder, Joshua G. Pierce

Version 1 posted 09 April 2018

795

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Biological and Medicinal Chemistry

Working Paper

Permeability Through Bacterial Porins Dictates Whole Cell Compound Accumulation

Silvia Acosta Gutiérrez, Igor Bodrenko, Matteo Ceccarelli

Version 1 posted 21 February 2020

508

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Biological and Medicinal Chemistry

Working Paper

A Synthetic Antibiotic Scaffold Effective Against Multidrug-Resistant Bacterial Pathogens

Matthew Mitcheltree, Amarnath Pisipati, Egor A. Syroegin, Katherine J. Silvestre, Dorota Klepacki, Jeremy Mason, Daniel W. Terwilliger, Giambattista Testolin, Aditya R. Pote, Kelvin J. Y. Wu, Richard Porter Ladley, Kelly Chatman, Alexander S. Mankin, Yury S. Polikanov, Andrew G. Myers

Version 1 posted 30 March 2021

939

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2

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Catalysis

Working Paper

Engineering P450 TamI as an Iterative Biocatalyst for Selective Late-Stage C-H Functionalization and Epoxidation of Tirandamycin Antibiotics

Rosa V. Espinoza, Kersti Caddell Haatveit, S. Wald Grossman, Jin Yi Tan, Caylie A. McGlade, Yogan Khatri, Sean A. Newmister, Jennifer J. Schmidt, Marc Garcia-Borràs, John Montgomery, Kendall N Houk, David H. Sherman

Version 1 posted 16 March 2021

464

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Biological and Medicinal Chemistry

Working Paper

Molecular Basis of Iterative C–H Oxidation by TamI, a Multifunctional P450 Monooxygenase from the Tirandamycin Biosynthetic Pathway

Sean A. Newmister, Kinshuk Raj Srivastava, Rosa V. Espinoza, Kersti Caddell Haatveit, Yogan Khatri, Rachel M. Martini, Marc Garcia-Borràs, Larissa M. Podust, Kendall N Houk, David H. Sherman

Version 1 posted 27 July 2020

430

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Organic Chemistry

Working Paper

Total Synthesis of Tiacumicin B: Implementing H-bond-Directed Acceptor Delivery for Highly Selective beta-Glycosylations

Stephanie Norsikian, cedric Tresse, Marc François-Eude, Louis Jeanne-Julien, Guillaume Masson, Vincent Servajean, Grégory Genta-Jouve, Jean-Marie Beau, Emmanuel Roulland

Version 1 posted 20 December 2019

674

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54 results in antibiotics in Keywords: antibiotics

Synthesis and Biological Evaluation of Iodinated Fidaxomicin Antibiotics

An Experimental Toolbox for Structure-Based Hit Discovery for P. Aeruginosa FabF, a Promising Target for Antibiotics

Synthetic Studies with the Brevicidine and Laterocidine Lipopeptide Antibiotics Including Analogues with Enhanced Properties and in vivo Efficacy

A Practical, Component-Based Synthetic Route to Methylthiolincosamine Permitting Facile Northern-Half Diversification of Lincosamide Antibiotics

Synthesis and Biological Evaluation of the Antimicrobial Natural Product Lipoxazolidinone A

Permeability Through Bacterial Porins Dictates Whole Cell Compound Accumulation

A Synthetic Antibiotic Scaffold Effective Against Multidrug-Resistant Bacterial Pathogens

Engineering P450 TamI as an Iterative Biocatalyst for Selective Late-Stage C-H Functionalization and Epoxidation of Tirandamycin Antibiotics

Molecular Basis of Iterative C–H Oxidation by TamI, a Multifunctional P450 Monooxygenase from the Tirandamycin Biosynthetic Pathway

Total Synthesis of Tiacumicin B: Implementing H-bond-Directed Acceptor Delivery for Highly Selective beta-Glycosylations

54 results in Keywords: antibiotics