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Physical Chemistry

Working Paper

The Properties of α-Synuclein Secondary Nuclei are Dominated by the Solution Conditions Rather than the Seed Fibril Strain

Alessia Peduzzo, Sara Linse, Alexander Buell

Version 1 posted 04 September 2019

507

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1

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Biological and Medicinal Chemistry

Working Paper

An Anthrone-Based Kv7.2/7.3 Channel Blocker with Improved Properties for the Investigation of Psychiatric and Neurodegenerative Disorders

Jacob Porter, Oscar Vivas-Rodriguez, C. David Weaver, Eamonn Dickson, Abdulmohsen Alsafran, Elliot DiMilo, Leggy Arnold, Chris Dockendorff

Version 1 posted 10 June 2019

556

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Analytical Chemistry

Working Paper

TD GC-MS and UPLC-MS methods to discover differentially expressed metabolites in sebum

Thomas D. Hoare, Caitlin Walton-Doyle, Katherine A. Hollywood, Eleanor Sinclair, Drupad K. Trivedi, Perdita Barran

Version 1 posted 13 December 2023

248

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Analytical Chemistry

Working Paper

Cyclic Ion Mobility-Mass Spectrometry and Tandem Collision Induced Unfolding for Quantification of Elusive Protein Biomarkers

Devin Makey, Varun Gadkari, Robert Kennedy, Brandon Ruotolo

Version 1 posted 25 January 2024

399

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Analytical Chemistry

Working Paper

Interpretable machine learning on metabolomics data reveals biomarkers for Parkinson’s disease

J. Diana Zhang, Chonghua Xue, Vijaya B. Kolachalama, William A. Donald

Version 1 posted 08 December 2022

413

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Biological and Medicinal Chemistry

Working Paper

Assessing Vesicular Monoamine Transport and Toxicity Using Fluorescent False Neurotransmitters

Carlie A. Hoffman, Meghan Bucher, Joshua M. Bradner, Lauren Jonas, Kenny Igarza, Gary W. Miller

Version 1 posted 28 August 2020

549

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Biological and Medicinal Chemistry

Working Paper

Enhancing Inhibition of Both α-Synuclein Aggregation and Neuroinflammation: New Insights into the C-9 Modification of Doxycycline

Clémence Rose, Rodrigo Hernán Tomas-Grau, Brenda Zabala, Jean-Michel Brunel, Patrick P. Michel, Rosana Chehin, Rita Raisman-Vozari, Laurent Ferrié, Bruno Figadère

Version 2 posted 02 June 2023

321

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Biological and Medicinal Chemistry

Working Paper

Discovery and characterization of benzyloxy piperidine based dopamine 4 receptor antagonists

Kirsten Tolentino, Viktoriya Mashinson, Anish Vadukoot, Corey Hopkins

Version 1 posted 22 September 2021

238

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Biological and Medicinal Chemistry

Working Paper

Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable and Blood Brain Barrier Penetrant Prote-olysis Targeting Chimera Degrader of Leucine Rich Repeat Kinase 2

Xingui Liu, Alexia Kalogeropulou, Sofia Domingos, Nikolai Makukhin, Raja Nirujogi, Francois Singh, Natalia Shpiro, Anton Saalfrank, Esther Sammler, Ian Ganley, Rui Moreira, Dario Alessi, Alessio Ciulli

Version 2 posted 13 July 2022

4,448

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1

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Analytical Chemistry

Working Paper

Rapid Electrochemical Detection of Levodopa using Polyaniline-Modified Screen-Printed Electrodes for the Improved Management of Parkinson's Disease

Henrique Noguchi, Sarbjeet Kaur, Luiza Krettli, Pankaj Singla, Jake McClements, Helena Snyder, Robert Crapnell, Craig Banks, Katarina Novakovic, Inderpreet Kaur, Jonas Gruber, James Dawson, Marloes Peeters

Version 1 posted 18 August 2022

280

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Refine Search

11 results in Parkinson's disease in Keywords: Parkinson's disease

The Properties of α-Synuclein Secondary Nuclei are Dominated by the Solution Conditions Rather than the Seed Fibril Strain

An Anthrone-Based Kv7.2/7.3 Channel Blocker with Improved Properties for the Investigation of Psychiatric and Neurodegenerative Disorders

TD GC-MS and UPLC-MS methods to discover differentially expressed metabolites in sebum

Cyclic Ion Mobility-Mass Spectrometry and Tandem Collision Induced Unfolding for Quantification of Elusive Protein Biomarkers

Interpretable machine learning on metabolomics data reveals biomarkers for Parkinson’s disease

Assessing Vesicular Monoamine Transport and Toxicity Using Fluorescent False Neurotransmitters

Enhancing Inhibition of Both α-Synuclein Aggregation and Neuroinflammation: New Insights into the C-9 Modification of Doxycycline

Discovery and characterization of benzyloxy piperidine based dopamine 4 receptor antagonists

Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable and Blood Brain Barrier Penetrant Prote-olysis Targeting Chimera Degrader of Leucine Rich Repeat Kinase 2

Rapid Electrochemical Detection of Levodopa using Polyaniline-Modified Screen-Printed Electrodes for the Improved Management of Parkinson's Disease

11 results in Keywords: Parkinson's disease