Search

SuFEx-Enabled High-Throughput Medicinal Chemistry

Seiya Kitamura, Qinheng Zheng, Jordan L. Woehl, angelo solan, Emily Chen, Nicholas Dillon, Mitchell Hull, Miyako Kotaniguchi, Shinichi Kitamura, Victor Nizet, K. Barry Sharpless, Dennis Wolan

Version 1 posted 20 December 2019

927

Downloads

Biological and Medicinal Chemistry

Working Paper

Tele-Substitution Reactions in the Synthesis of a Promising Class of Antimalarials

Marat Korsik, Edwin Tse, David Smith, William Lewis, Peter J. Rutledge, Matthew Todd

Version 1 posted 06 May 2020

564

Downloads

1

Citations

Biological and Medicinal Chemistry

Working Paper

Medicinal Chemistry Database GDBMedChem

Mahendra Awale, Finton Sirockin, Nikolaus Stiefl, Jean-Louis Reymond

Version 1 posted 27 February 2019

820

Downloads

Chemical Education

Working Paper

Make a Molecule: A Synthetic Organic and Medicinal Chemistry Workshop for High School Students

Iain A. Stepek, Raphael Hofmann, Paula L. Nichols, Andrea Aschwanden, Christophe Eckard, Patrick Aschwanden, Jeffrey Bode

Version 1 posted 30 August 2019

825

Downloads

Biological and Medicinal Chemistry

Working Paper

Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated

Magalie Géraldy, Michael Morgen, Peter Sehr, Raphael R. Steimbach, Johannes Ridinger, Ina Oehme, Olaf Witt, Mauro S. Nogueira, Oliver Koch, Nikolas Gunkel, Aubry K. Miller, Mona Malz

Version 1 posted 06 December 2018

1,131

Downloads

Biological and Medicinal Chemistry

Working Paper

Synthesis and Structure–Activity Relationships of N-(4-Benzamidino)-Oxazolidinones–Potent and Selective Inhibitors of Kallikrein-Related Peptidase 6

Elena De Vita, Niels Smits, Helma van den Hurk, Elizabeth M. Beck, Joanne Hewitt, Gemma Baillie, Emily Russell, Andrew Pannifer, Véronique Hamon, Angus Morrison, Stuart P. McElroy, Philip Jones, Natalia A. Ignatenko, Nikolas Gunkel, Aubry K. Miller

Version 1 posted 16 September 2019

878

Downloads

Organic Chemistry

Working Paper

General Cyclopropane Assembly via Enantioselective Redox-Active Carbene Transfer to Aliphatic Olefins

Marc Montesinos-Magraner, Matteo Costantini, Rodrigo Ramirez-Contreras, Michael E. Muratore, Magnus J. Johansson, Abraham Mendoza

Version 1 posted 10 December 2018

1,470

Downloads

1

Citations

Biological and Medicinal Chemistry

Working Paper

Development of Inhibitors Against Mycobacterium Abscessus tRNA (m1G37) Methyltransferase (TrmD) Using Fragment-Based Approaches

Andrew J. Whitehouse, Sherine E. Thomas, Karen P. Brown, Alexander Fanourakis, Daniel Chan, M. Daben J. Libardo, Vitor Mendes, Helena I. M. Boshoff, R. Andres Floto, Chris Abell, Tom. L. Blundell, Anthony Coyne

Version 1 posted 16 May 2019

570

Downloads

Biological and Medicinal Chemistry

Working Paper

Rapid Elaboration of Fragments into Leads Applied to Bromodomain-3 Extra Terminal Domain

Luke Adams, Lorna E. Wilkinson-White, Menachem J. Gunzburg, Stephen J. Headey, Martin J. Scanlon, Ben Capuano, Joel P. Mackay, Bradley Doak

Version 1 posted 25 March 2020

726

Downloads

Biological and Medicinal Chemistry

Working Paper

A Web Tool for Calculating Substituent Descriptors Compatible with Hammett Sigma Constants

Peter Ertl

Version 1 posted 16 March 2021

1,302

Downloads

2

Citations

Refine Search

62 results in Medicinal chemistry in Keywords: Medicinal chemistry

SuFEx-Enabled High-Throughput Medicinal Chemistry

Tele-Substitution Reactions in the Synthesis of a Promising Class of Antimalarials

Medicinal Chemistry Database GDBMedChem

Make a Molecule: A Synthetic Organic and Medicinal Chemistry Workshop for High School Students

Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated

Synthesis and Structure–Activity Relationships of N-(4-Benzamidino)-Oxazolidinones–Potent and Selective Inhibitors of Kallikrein-Related Peptidase 6

General Cyclopropane Assembly via Enantioselective Redox-Active Carbene Transfer to Aliphatic Olefins

Development of Inhibitors Against Mycobacterium Abscessus tRNA (m1G37) Methyltransferase (TrmD) Using Fragment-Based Approaches

Rapid Elaboration of Fragments into Leads Applied to Bromodomain-3 Extra Terminal Domain

A Web Tool for Calculating Substituent Descriptors Compatible with Hammett Sigma Constants

62 results in Keywords: Medicinal chemistry