Organic Chemistry

Fluoro-bicyclo[1.1.1]pentanes

Authors

Abstract

After more than 20 years of trials, a practical scalable approach to fluoro-bicyclo[1.1.1]pentanes (19F-BCPs) has been developed. Physico-chemical properties of fluoro-bicyclo[1.1.1]pentanes have been studied, and the core was incorporated into the structure of the anti-inflammatory drug Flurbiprofen instead of the fluorophenyl ring.

Content

Thumbnail image of Manuscript.pdf

Supplementary material

Thumbnail image of SI.pdf
Supporting Information
SI