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The Clinically Used Iron Chelator Deferasirox is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases

Manfred Jung, Martin Roatsch, Inga Hoffmann, Martine I. Abboud, Rebecca L. Hancock, Hanna Tarhonskaya, Kuo-Feng Hsu, Sarah E. Wilkins, Tzu-lan Yeh, Kerstin Lippl, Kerstin Serrer, Isabelle Moneke, Theresa D. Ahrens, Dina Robaa, Sandra Wenzler, Henriette Franz, Wolfgang Sippl, Silke Lassmann, Sven Diederichs, Erik Schleicher, Christopher J. Schofield, Akane Kawamura, Roland Schüle

Version 3 posted 09 July 2019

1,215

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Biological and Medicinal Chemistry

Working Paper

First fluorescent acetylspermidine deacetylation assay for HDAC10 identifies selective inhibitors with cellular target engagement

Daniel Herp, Johannes Ridinger, Dina Robaa, Stephen A. Shinsky, Karin Schmidtkunz, Talha Z. Yesiloglu, Theresa Bayer, Raphael R. Steimbach, Corey J. Herbst-Gervasoni, Annika Merz, Christophe Romier, Peter Sehr, Nikolas Gunkel, Aubry K. Miller, David W. Christianson, Ina Oehme, Wolfgang Sippl, Manfred Jung

Version 4 posted 30 March 2022

1,327

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Inorganic Chemistry

Working Paper

Metal Complexes as a Promising Source for New Antibiotics

Angelo Frei, Johannes Zuegg, Alysha Elliott, Murray Baker, Stefan Bräse, Christopher Brown, Feng Chen, Christopher Dowson, Gilles Dujardin, Nicole Jung, A. Paden King, Ahmed Mansour, Massimiliano Massi, John Moat, Heba Mohamed, Anna Renfrew, Peter J. Rutledge, Peter J. Sadler, Matthew Todd, Charlotte E. Willans, Justin J. Wilson, Matthew Cooper, Mark A. T. Blaskovich

Version 2 posted 22 October 2019

1,001

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Analytical Chemistry

Working Paper

One-step hydrothermal synthesis of 4-Metylimidazole Decorated Carbon Nanoparticles and Their Fluorescence Enhancement Sensing of Heavy Metal Ions

Tak Kim, Jung-ho Yun, Sue Boyd, Christopher Brown

Version 1 posted 06 July 2021

192

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Organic Chemistry

Working Paper

Enantioselective Synthesis of Cyclopropanone Equivalents and Application to the Synthesis of β-Lactams

Christopher M. Poteat, Yujin Jang, Myunggi Jung, John D. Johnson, Rachel G. Williams, Vincent Lindsay

Version 1 posted 27 December 2019

1,079

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Biological and Medicinal Chemistry

Working Paper

Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity

Salma Darwish, Ehab Ghazy, Tino Heimburg, Daniel Herp, Patrik Zeyen, Rabia Salem-Altintas, Johannes Ridinger, Karin Schmidtkunz, Dina Robaa, Frank Erdmann, Matthias Schmidt, Christophe Romier, Manfred Jung, Ina Oehme, Wolfgang Sippl

Version 2 posted 25 May 2022

788

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2

Citations

Catalysis

Working Paper

Importance of Site Diversity and Connectivity in Electrochemical CO Reduction on Cu

Chansol Kim, Nitish Govindarajan, Sydney Hemenway, Junho Park, Anya Zoraster, Calton Kong, Rajiv Prabhakar, Joel Varley, Hee-Tae Jung, Christopher Hahn, Joel Ager

Version 1 posted 18 December 2023

458

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Organic Chemistry

Working Paper

Supporting Sustainability of Chemistry by Linking Research Data with Physically Preserved Research Materials

Chia-Lin Lin, Pei-Chi Huang, Simone Graessle, Christoph Grathwol, Pierre Tremouilhac, Sylvia Vanderheiden, Patrick Hodapp, Sonja Herres-Pawlis, Alexander Hoffmann, Fabian Fink, Georg Manolikakes, Till Opatz, Andreas Link, M. Manuel B. Marques, Lena J. Daumann, Manuel Tsotsalas, Frank Biedermann, Hatice Mutlu, Eric Täuscher, Felix Bach, Tim Drees, Steffen Neumann, Nicole Jung, Stefan Bräse

Version 1 posted 04 July 2023

278

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1

Citations

Biological and Medicinal Chemistry

Working Paper

Structure-Reactivity Relationships on Substrates and Inhibitors of the Lysine Deacylase Sirtuin 2 from Schistosoma Mansoni (SmSirt2)

Daria Monaldi, Dante Rotili, Julien Lancelot, Martin Marek, Nathalie Wössner, Alessia Lucidi, Daniela Tomaselli, Elizabeth Ramos-Morales, Christophe Romier, Raymond J. Pierce, Antonello Mai, Manfred Jung

Version 2 posted 02 August 2019

1,011

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Materials Chemistry

Working Paper

Production of Magnetic Arsenic-Phosphorus Alloy Nanoribbons with Small Band Gaps and High Hole Conductivities

Fengfei Zhang, Eva Aw, Alexander Eaton, Rebecca Shutt, Juhwan Lim, Jung Ho Kim, Thomas Macdonald, Cesar De Leon Reyes, Arjun Ashoka, Raj Pandya, Oliver Payton, Loren Picco, Caroline Knapp, Akshay Rao, Christopher Howard, Adam Clancy

Version 1 posted 29 March 2023

294

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17 results in Christoph Jung in Authors: Christoph Jung

The Clinically Used Iron Chelator Deferasirox is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases

First fluorescent acetylspermidine deacetylation assay for HDAC10 identifies selective inhibitors with cellular target engagement

Metal Complexes as a Promising Source for New Antibiotics

One-step hydrothermal synthesis of 4-Metylimidazole Decorated Carbon Nanoparticles and Their Fluorescence Enhancement Sensing of Heavy Metal Ions

Enantioselective Synthesis of Cyclopropanone Equivalents and Application to the Synthesis of β-Lactams

Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity

Importance of Site Diversity and Connectivity in Electrochemical CO Reduction on Cu

Supporting Sustainability of Chemistry by Linking Research Data with Physically Preserved Research Materials

Structure-Reactivity Relationships on Substrates and Inhibitors of the Lysine Deacylase Sirtuin 2 from Schistosoma Mansoni (SmSirt2)

Production of Magnetic Arsenic-Phosphorus Alloy Nanoribbons with Small Band Gaps and High Hole Conductivities

17 results in Authors: Christoph Jung