Working Paper
Authors
- Sampad Jana ,
- Sweta Adhikari ,
- Michael Cox ,
- Sudeshna Roy
University of Mississippi, School of Pharmacy
Abstract
Here, we show that 1-fluoronitroalkenes can serve as synthetic surrogates of 1-fluoroalkynes in [3+2] cycloaddition reactions with organic azides facilitated by a catalytic amount of trifloroacetic acid. This work provides the first regioselective method to access 4-fluoro-1,5-substituted-1,2,3-triazoles.
Version notes
This is the third revised version.
Content

Supplementary material

Supporting Information ChemRxiv v3