Catalysis

Fluorinated 1,2,3-Triazoles from α-Fluoronitroalkenes as Surrogates of α-Fluoroalkynes via Regioselective Cycloaddition Reactions with Organic Azides

Authors

Abstract

Here we show that 1-fluoronitroalkenes can serve as synthetic surrogates of 1-fluoroalkynes in [3+2] cycloaddition reactions with organic azides facilitated by a catalytic amount of trifluoroacetic acid.

Version notes

This is the first submission to Chemrxiv.

Content

Thumbnail image of Fluoronitroalkene to Fluorotriazole_Final_v2_without watermark.pdf

Supplementary material

Thumbnail image of Supporting information V16.pdf
Supporting information V16