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    2019 results for search term: Christopher Southan

    Category: Biological and Medicinal Chemistry
    ,
    Working Paper
    , Title:

    An open-access tool for designing drug control into engineered proteins

    , Authors: Sam M Ireland, Christopher Southan, Alazane Dominguez-Monedero, Simon D. Harding, Joanna L. Sharman, Jamie A. Davies
    Version 1 posted 06 April 2018

    Extract found to contain search terms

    Sam M. Ireland #, Christopher Southan *, Alazne Dominguez-Monedero, Simon D. Harding, Joanna L. Sharman & Jamie A. Davies. Centre for Discovery Brain Sciences, Deanery for Biomedical Sciences, University of Edinburgh, Edinburgh EH8 9XD, UK. # Current address: Biomolecular Structure & Modelling Unit, Institute of Structural and Molecular Biology, Division of Biosciences, University College London, London WC1E 6BT, UK * Address for correspondence: Dr Christopher Southan , Centre for Discovery Brain Sciences, Deanery for Biomedical Sciences, University of Edinburgh, Edinburgh EH8 9XD, UK. [email protected] ORCID IDs: Ireland S.M., 0000-0001-8248-7614 Southan
    934
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    Category: Biological and Medicinal Chemistry
    ,
    Working Paper
    , Title:

    Challenges of Connecting Chemistry to Pharmacology: Perspectives from Curating the IUPHAR/BPS Guide to PHARMACOLOGY

    , Authors: Christopher Southan, Joanna L Sharman, Elena Faccenda, Adam J Pawson, Simon D Harding, Jamie A Davies
    Version 1 posted 03 May 2018

    Extract found to contain search terms

    1 02 May 2018 submission version Challenges of connecting chemistry to pharmacology: perspectives from curating the IUPHAR/BPS Guide to PHARMACOLOGY Christopher Southan *, Joanna L Sharman, Elena Faccenda, Adam J Pawson, Simon D Harding and Jamie A Davies, IUPHAR/BPS Guide to PHARMACOLOGY, Centre for Discovery Brain Sciences, Deanery of Biomedical Sciences, University of Edinburgh, UK. * Address for correspondence: Dr Christopher Southan , Centre for Discovery Brain Sciences, Deanery of Biomedical Sciences, University of Edinburgh, Edinburgh EH8 9XD, UK. [email protected] ORCID IDs: Southan
    923
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    Category: Biological and Medicinal Chemistry
    ,
    Working Paper
    , Title:

    Will the Chemical Probes Please Stand Up?

    , Authors: Ctibor Škuta, Christopher Southan, Petr Bartunek
    Version 2 posted 02 July 2021

    Extract found to contain search terms

    Sharman, C. Southan and J. A. Davies, Br. J. Pharmacol., 2019, 176, S229–S246. 24 S. P. H. Alexander, D. Fabbro, E. Kelly, A. Mathie, J. A. Peters, E. L. Veale, J. F. Armstrong, E. Faccenda, S. D. Harding, A. J. Pawson, J. L. Sharman, C. Southan and J. A. Davies, Br. J. Pharmacol., 2019, 176, S247–S296. 25 S. P. H. Alexander, D. Fabbro, E. Kelly, A. Mathie, J. A. Peters, E. L. Veale, J. F. Armstrong, E. Faccenda, S. D. Harding, A. J. Pawson, J. L. Sharman, C. Southan and J. A. Davies, Br. J. Pharmacol., 2019, 176, S297–S396. 26 S. P. H. Alexander, E. Kelly, A. Mathie, J. A. Peters, E. L. Veale, J. F. Armstrong, E. Faccenda, S. D. Harding, A. J. Pawson, J. L. Sharman, C. Southan
    619
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    Category: Biological and Medicinal Chemistry
    ,
    Working Paper
    , Title:

    Identification of potential anti-COVID-19 drug leads from Medicinal Plants through Virtual High-Throughput Screening

    , Authors: Rohoullah Firouzi, Mitra Ashouri
    Version 1 posted 18 April 2022

    Extract found to contain search terms

    Lett. 2021, 12, 11850−11857. https://doi.org/10.1021/acs.jpclett.1c03380 (23) Montserrat Bárcena, Christopher O. Barnes, Martin Beck, Pamela J. Bjorkman, Bruno Canard, George F. Gao, Yunyun Gao, Rolf Hilgenfeld, Gerhard Hummer, Ardan Patwardhan, Gianluca Santoni, Erica Ollmann Saphire, Christiane Schaftzel, Sharon L. Schendel, Janet L. Smith, Andrea Thorn, David Veesler, Peijun Zhang and Qiang Zhou, Structural biology in the fight against COVID-19, Nat. Struct. Mol. Biol. 2021, 28, 2-7. https://doi.org/10.1038/s41594- 020-00544-8 (22) Sean Ekins, Melina Mottin, Paulo R.P.S. Ramos, Bruna K.P. Sousa, Bruno Junior Neves, Daniel H. Foil, Kimberley M. Zorn, Rodolpho C. Braga, Megan Coffee, Christopher Southan
    388
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    Category: Biological and Medicinal Chemistry
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    Working Paper
    , Title:

    BindingDB in 2024: a FAIR Knowledgebase of Protein-Small Molecule Binding Data

    , Authors: Tiqing Liu, Linda Hwang, Stephen K Burley, Carmen I Nitsche, Christopher Southan, W. Patrick Walters, Michael K. Gilson
    Version 1 posted 13 September 2024

    Extract found to contain search terms

    1 BindingDB in 2024: a FAIR Knowledgebase of Protein-Small Molecule Binding Data Tiqing Liu1, Linda Hwang1, Stephen K. Burley2, Carmen I. Nitsche3, Christopher
    349
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    Category: Biological and Medicinal Chemistry
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    Working Paper
    , Title:

    Pose Classification using 3D Atomic Structure-Based Neural Networks Applied to Ion Channel-Ligand Docking

    , Authors: Heesung Shim, Hyojin Kim, Jonathan Allen, Heike Wulff
    Version 1 posted 29 March 2022

    Extract found to contain search terms

    .; Iwata, S., Overcoming the challenges of membrane protein crystallography. Curr Opin Struct Biol 2008, 18 (5), 581-6. 35. Alexander, S. P.; Peters, J. A.; Kelly, E.; Marrion, N. V.; Faccenda, E.; Harding, S. D.; Pawson, A. J.; Sharman, J. L.; Southan , C.; Davies, J. A.; Collaborators, C., THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Ligand-gated ion channels. Br J Pharmacol 2017, 174 Suppl 1, S130-S159. 36. Alexander, S. P.; Striessnig, J.; Kelly, E.; Marrion, N. V.; Peters, J. A.; Faccenda, E.; Harding, S. D.; Pawson, A. J.; Sharman, J. L.; Southan
    303
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    Category: Theoretical and Computational Chemistry
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    Working Paper
    , Title:

    Identification of the Core Chemical Structure in SureChEMBL Patents

    , Authors: Maria J. Falaguera, Jordi Mestres
    Version 1 posted 01 February 2021

    Extract found to contain search terms

    Availability The SureChEMBL subset of molecules claimed by pharmacological US patents is available for download at ftp://ftp.ebi.ac.uk/pub/databases/chembl/SureChEMBLccs. Conflicts of interest There are no conflicts to declare. References 1. G. Papadatos, M. Davies, N. Dedman, J. Chambers, A. Gaulton, J. Siddle, R. Koks, S. A. Irvine, J. Pettersson, N. Goncharoff, A. Hersey and J. P. Overington, Nucleic Acids Res., 2016, 44, D1220–D1228. 2. S. Senger, J. Cheminform., 2017, 9, 26. 3. C. Southan
    691
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    Category: Organic Chemistry
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    Working Paper
    , Title:

    Fulgazepam: A Fulgimide-Based Potentiator of GABAA Receptors

    , Authors: Karin Rustler, Galyna Maleeva, Alexandre M. J. Gomila, Pau Gorostiza, Piotr Bregestovski, Burkhard Koenig
    Version 1 posted 30 September 2019

    Extract found to contain search terms

    Soc. 2014, 136, 2178-2191. [5] K. Hüll, J. Morstein, D. Trauner, Chem. Rev. 2018, 118, 10710-10747. [6] J. Broichhagen, J. A. Frank, D. Trauner, Acc. Chem. Res. 2015, 48, 1947-1960. [7] T. Lynagh, S. A. Pless, Front. Physiol. 2014, 5 (160), 1-12. [8] S. P. H. Alexander, J. A. Peters, E. Kelly, N. Marrion, H. E. Benson, E. Faccenda, A. J. Pawson, J. L. Sharman, C. Southan
    622
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