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Theoretical and Computational Chemistry

Working Paper

Cheminformatics Modeling of Closantel Analogues for Treating River Blindness

Melaine A. Kuenemann, Phyo Phyo Zin, Sravya Kuchibhotla, Denis Fourches

Version 1 posted 17 January 2020

491

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Organic Chemistry

Working Paper

Deep Alanine Scanning Reveals Potent Multi-alanine-substituted Protein–protein Interaction Inhibitors

Xiyun Ye, Yen-Chun Lee, Zachary P. Gates, Yingjie Ling, Jennifer Mortensen, Fan-Shen Yang, Yu-Shan Lin, Bradley Pentelute

Version 1 posted 21 January 2021

784

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1

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Biological and Medicinal Chemistry

Working Paper

Role of Guanidinium-Carboxylate Interaction in Enzyme Inhibition with Implication for Drug Design

Aswathy Muttathukattil, Sriraksha Srinivasan, Antarip Halder, Govardhan Reddy

Version 1 posted 02 July 2019

491

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Organic Chemistry

Working Paper

Novel non-canonical strigolactone analogs highlight selectivity for stimulating germination in two Phelipanche ramosa populations

Suzanne Daignan Fornier, Alexandre de Saint Germain, Pascal Retailleau, Jean-Paul Pillot, Quentin Taulera, Lucile Andna, Laurence Miesch, Soizic Rochange, Jean-Bernard Pouvreau, François-Didier Boyer

Version 1 posted 14 March 2022

310

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Biological and Medicinal Chemistry

Working Paper

Further synthesis and biological characterization of a series of 2-sulfonamidebenzamides as allosteric modulators of MrgX1

Swagat Sharma, Qi Peng, Anish Vadukoot, Christopher Aretz, Aaron Jensen, Alexander Wallick, Xinzhong Dong, Corey Hopkins

Version 1 posted 28 July 2021

233

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Biological and Medicinal Chemistry

Working Paper

Identification of Novel MR1 Ligands Derived from Herbal Medicines by MR1-Presentation Reporter Screening and Their Structure-Activity Relationship

Takuro Matsuoka, Akira Hattori, Shinya Oishi, Norihito Arichi, Hideaki Kakeya, Sho Yamasaki, Hiroaki Ohno, Shinsuke Inuki

Version 1 posted 07 November 2022

411

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Biological and Medicinal Chemistry

Working Paper

A photo-SAR study of photoswitchable azobenzene tubulin-inhibiting antimitotics identifying a general method for near-quantitative photocontrol

Martin Reynders, Małgorzata Garścia, Adrian Müller-Deku, Maximilian Wranik, Kristina Krauskopf, Luis de la Osa de la Rosa, Konstantin Schaffer, Anna Jötten, Alexander Rode, Valentin Stierle, Yvonne Kraus, Benedikt Baumgartner, Ahmed Ali, Andrei Bubeneck, Trina Seal, Michel Steinmetz, Philipp Paulitschke, Oliver Thorn-Seshold

Version 1 posted 08 May 2024

147

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Biological and Medicinal Chemistry

Working Paper

Selective Carbonic Anhydrase IX and XII Inhibitors Based Around a Functionalized Coumarin Scaffold

Bader Huwaimel, Sravan Jonnalagadda, Shirisha Jonnalagadda, Shikha Kumari, Alessio Nocentinic, Claudiu Supuran, Trippier Paul

Version 1 posted 30 January 2023

204

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Biological and Medicinal Chemistry

Working Paper

Assessing the activity of benzodioxol, phenol and aniline derivatives as radical trapping antioxidants that inhibit ferroptosis

Helene B. E. Schricker, Mohamed M. Mouzayek, Jonas Wanninger, Hala Zahran, Kyra Lützel, Anna V. Milton, Eikan Mishima, Toshitaka Nakamura, Bettina Proneth, Marcus Conrad, David B. Konrad

Version 1 posted 28 March 2024

424

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Biological and Medicinal Chemistry

Working Paper

Structure-activity relationship study of splicing modulators on Hsh155/SF3B1 through chemical synthesis and yeast genetics

Jacob Beard, Sierra Love, John Schmitz, Aaron Hoskins, Kazunori Koide

Version 1 posted 10 April 2024

166

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Refine Search

22 results in structure-activity relationship in Keywords: structure-activity relationship

Cheminformatics Modeling of Closantel Analogues for Treating River Blindness

Deep Alanine Scanning Reveals Potent Multi-alanine-substituted Protein–protein Interaction Inhibitors

Role of Guanidinium-Carboxylate Interaction in Enzyme Inhibition with Implication for Drug Design

Novel non-canonical strigolactone analogs highlight selectivity for stimulating germination in two Phelipanche ramosa populations

Further synthesis and biological characterization of a series of 2-sulfonamidebenzamides as allosteric modulators of MrgX1

Identification of Novel MR1 Ligands Derived from Herbal Medicines by MR1-Presentation Reporter Screening and Their Structure-Activity Relationship

A photo-SAR study of photoswitchable azobenzene tubulin-inhibiting antimitotics identifying a general method for near-quantitative photocontrol

Selective Carbonic Anhydrase IX and XII Inhibitors Based Around a Functionalized Coumarin Scaffold

Assessing the activity of benzodioxol, phenol and aniline derivatives as radical trapping antioxidants that inhibit ferroptosis

Structure-activity relationship study of splicing modulators on Hsh155/SF3B1 through chemical synthesis and yeast genetics

22 results in Keywords: structure-activity relationship