Search

Theoretical and Computational Chemistry

Working Paper

Cheminformatics Modeling of Closantel Analogues for Treating River Blindness

Melaine A. Kuenemann, Phyo Phyo Zin, Sravya Kuchibhotla, Denis Fourches

Version 1 posted 17 January 2020

488

Downloads

Biological and Medicinal Chemistry

Working Paper

Role of Guanidinium-Carboxylate Interaction in Enzyme Inhibition with Implication for Drug Design

Aswathy Muttathukattil, Sriraksha Srinivasan, Antarip Halder, Govardhan Reddy

Version 1 posted 02 July 2019

489

Downloads

Organic Chemistry

Working Paper

Deep Alanine Scanning Reveals Potent Multi-alanine-substituted Protein–protein Interaction Inhibitors

Xiyun Ye, Yen-Chun Lee, Zachary P. Gates, Yingjie Ling, Jennifer Mortensen, Fan-Shen Yang, Yu-Shan Lin, Bradley Pentelute

Version 1 posted 21 January 2021

772

Downloads

1

Citations

Organic Chemistry

Working Paper

Identification of a privileged scaffold for inhibition of sterol transport proteins through the synthesis and ring distortion of diverse, pseudo-natural products

Frederik Simonsen Bro, Laura Depta, Nienke Dekker, Hogan Bryce-Rogers, Kaia Præstegaard, Tino Petersson, Thomas Whitmarsh-Everiss, Mariusz Kubus, Luca Laraia

Version 1 posted 24 July 2024

258

Downloads

Catalysis

Working Paper

Water-assisted generation of catalytic interface: The case of interfacial Pt-FeOx(OH)y sites active in preferential carbon monoxide oxidation

Ilia I. Sadykov, Dennis Palagin, Frank Krumeich, Igor V. Plokhikh, Jeroen A. van Bokhoven, Maarten Nachtegaal, Olga V. Safonova

Version 1 posted 05 September 2023

163

Downloads

Biological and Medicinal Chemistry

Working Paper

Comprehensive cell biological investigation of cytochalasin B derivatives with distinct activities on the actin network

Mervic D. Kagho, Katharina Schmidt, Christopher Lambert, Thomas Kaufmann, Lili Jia, Jan Faix, Klemens Rottner, Marc Stadler, Theresia Stradal, Philipp Klahn

Version 2 posted 24 June 2024

240

Downloads

Biological and Medicinal Chemistry

Working Paper

Structure-activity relationship study of splicing modulators on Hsh155/SF3B1 through chemical synthesis and yeast genetics

Jacob Beard, Sierra Love, John Schmitz, Aaron Hoskins, Kazunori Koide

Version 1 posted 10 April 2024

156

Downloads

Biological and Medicinal Chemistry

Working Paper

Assessing the activity of benzodioxol, phenol and aniline derivatives as radical trapping antioxidants that inhibit ferroptosis

Helene B. E. Schricker, Mohamed M. Mouzayek, Jonas Wanninger, Hala Zahran, Kyra Lützel, Anna V. Milton, Eikan Mishima, Toshitaka Nakamura, Bettina Proneth, Marcus Conrad, David B. Konrad

Version 1 posted 28 March 2024

409

Downloads

Biological and Medicinal Chemistry

Working Paper

Improvement of Inhibitors of the Macrophage Infectivity Potentiator Protein from Trypanosoma cruzi, Burkholderia pseudomallei, and Legionella pneumophila – a Comparison

Theresa Lohr, Carina Herbst, Nicole Bzdyl, Christopher Jenkins, Nicolas Scheuplein, Wisely Oki Sugiarto, Jacob Whittaker, Albert Guskov, Isobel Norville, Ute Hellmich, Felix Hausch, Mitali Sakar-Tyson, Christoph Sotriffer, Ulrike Holzgrabe

Version 1 posted 27 May 2024

73

Downloads

Catalysis

Working Paper

Boundary Conditions for Promotion versus Poisoning in Copper-Gallium-based CO2–to–Methanol Hydrogenation Catalysts

Jan L. Alfke, Maria Tejeda-Serrano, Sumant Phadke, Andrei Tereshchenko, Terry Z. H. Gani, Lukas Rochlitz, Seraphine B. X. Y. Zhang, Lin Lin, Christophe Copéret, Olga V. Safonova

Version 3 posted 01 February 2024

684

Downloads

Refine Search

22 results in structure-activity relationship in Keywords: structure-activity relationship

Cheminformatics Modeling of Closantel Analogues for Treating River Blindness

Role of Guanidinium-Carboxylate Interaction in Enzyme Inhibition with Implication for Drug Design

Deep Alanine Scanning Reveals Potent Multi-alanine-substituted Protein–protein Interaction Inhibitors

Identification of a privileged scaffold for inhibition of sterol transport proteins through the synthesis and ring distortion of diverse, pseudo-natural products

Water-assisted generation of catalytic interface: The case of interfacial Pt-FeOx(OH)y sites active in preferential carbon monoxide oxidation

Comprehensive cell biological investigation of cytochalasin B derivatives with distinct activities on the actin network

Structure-activity relationship study of splicing modulators on Hsh155/SF3B1 through chemical synthesis and yeast genetics

Assessing the activity of benzodioxol, phenol and aniline derivatives as radical trapping antioxidants that inhibit ferroptosis

Improvement of Inhibitors of the Macrophage Infectivity Potentiator Protein from Trypanosoma cruzi, Burkholderia pseudomallei, and Legionella pneumophila – a Comparison

Boundary Conditions for Promotion versus Poisoning in Copper-Gallium-based CO2–to–Methanol Hydrogenation Catalysts

22 results in Keywords: structure-activity relationship