Search

Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor

Anna Skwarska, Ewen Calder, Deborah Sneddon, Hannah Bolland, Maria Odyniec, Ishna N. Mistry, Jennifer Martin, Lisa Folkes, Ester M. Hammond, Stuart Conway

Version 2 posted 23 March 2021

1,126

Downloads

Biological and Medicinal Chemistry

Working Paper

Hypoxia-Activated Small Molecule-Induced Gene Expression

Sarah L. Collins, Jaideep Saha, Laure C. Bouchez, Ester M. Hammond, Stuart Conway

Version 1 posted 24 July 2018

720

Downloads

Biological and Medicinal Chemistry

Working Paper

Click Activated Protodrugs Against Cancer Increase the Therapeutic Potential of Chemotherapy through Local Capture and Activation

Kui Wu, Nathan Yee, Sangeetha Srinivasan, Amir Mahmoodi, Michael Zakharian, Jose M. Mejia Oneto, Maksim Royzen

Version 2 posted 02 November 2020

2,652

Downloads

Inorganic Chemistry

Working Paper

Direct Measurement of the Visible to UV Photodissociation Processes for the PhotoCORM TryptoCORM

Rosaria Cercola, Kaitlyn Fischer, Summer Scherman, etienne garand, Natalie Wong, Anders Hammarback, Jason Lynam, Ian Fairlamb, Caroline E. H. Dessent

Version 1 posted 23 December 2019

417

Downloads

Organic Chemistry

Working Paper

Signal-triggered release of allyl-caged tertiary amine drugs from polymer hydrogels

Rienk Eelkema, Benjamin Klemm, Magherita Tavasso, Irene Piergentili, Max Satijn, Tobias Breve, Pouyan Boukany

Version 1 posted 31 January 2024

236

Downloads

1

Citations

Organic Chemistry

Working Paper

Bioresponsive pseudoGlucosinolates (psGSLs) release Isothiocyanates (ITCs) in the Presence of Nitroreductases

Claire C. Jimidar, Charity S. G. Ganskow, Mervic D. Kagho, Aishi Chakrabarti, Lorenz Wiese, Michael Zollo, Ulrike Beutling, Leona C. Cesar, Julia Morud, Mark Brönstrup, Stephan A. Sieber, Stephan M. Hacker, Philipp Klahn

Version 2 posted 08 July 2024

636

Downloads

Biological and Medicinal Chemistry

Working Paper

HSA-hijacking nanobinders built on bioresponsive prodrugs for combined cancer chemoimmunotherapy

Matilde Tubertini, Luca Menilli, Celeste Milani, Cecilia Martini, Maria Luisa Navacchia, Marta Nugnes, Manuela Bartolini, Marina Naldi, Daniele Tedesco, Elisa Martella, Andrea Guerrini, Claudia Ferroni, Francesca Moret, Greta Varchi

Version 1 posted 24 August 2023

125

Downloads

1

Citations

Biological and Medicinal Chemistry

Working Paper

Nitroreductase-Mediated Release of Inhibitors of Lysine-Specific Demethylase 1 (LSD1) from Prodrugs in Transfected Acute Myeloid Leukaemia Cells

Manfred Jung, Eva-Maria Herrlinger, Mirjam Hau, Desiree M. Redhaber, Gabriele Greve, Dominica Willmann, Simon Steimle, Michael Müller, Michael Lübbert, Cornelius Miething, Roland Schüle

Version 1 posted 24 October 2019

952

Downloads

Catalysis

Working Paper

Mild Organic Base-Catalyzed Primary Alcohol-Selective Aroylation Reaction Using N-Aroylcarbazoles for Underexplored Prodrugs

Yasuaki Morita, Bubwoong Kang, Rubi Nakashima, Yuki Shimizu, Asumi Sakai, Maiko Moriguchi, Yoko Yasuno, Tetsuya Satoh, Tetsuro Shinada, Masaki Kuse

Version 1 posted 09 June 2020

713

Downloads

Biological and Medicinal Chemistry

Working Paper

Tetrazine-Triggered Bioorthogonal Cleavage of trans-Cyclooctene-Caged Phenols Using a Minimal Self-Immolative Linker Strategy

Patrick Keppel, Barbara Sohr, Walter Kuba, Philipp Skrinjar, Jonathan Carlson, Hannes Mikula

Version 1 posted 23 June 2022

534

Downloads

Refine Search

12 results in prodrugs in Keywords: prodrugs

Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor

Hypoxia-Activated Small Molecule-Induced Gene Expression

Click Activated Protodrugs Against Cancer Increase the Therapeutic Potential of Chemotherapy through Local Capture and Activation

Direct Measurement of the Visible to UV Photodissociation Processes for the PhotoCORM TryptoCORM

Signal-triggered release of allyl-caged tertiary amine drugs from polymer hydrogels

Bioresponsive pseudoGlucosinolates (psGSLs) release Isothiocyanates (ITCs) in the Presence of Nitroreductases

HSA-hijacking nanobinders built on bioresponsive prodrugs for combined cancer chemoimmunotherapy

Nitroreductase-Mediated Release of Inhibitors of Lysine-Specific Demethylase 1 (LSD1) from Prodrugs in Transfected Acute Myeloid Leukaemia Cells

Mild Organic Base-Catalyzed Primary Alcohol-Selective Aroylation Reaction Using N-Aroylcarbazoles for Underexplored Prodrugs

Tetrazine-Triggered Bioorthogonal Cleavage of trans-Cyclooctene-Caged Phenols Using a Minimal Self-Immolative Linker Strategy

12 results in Keywords: prodrugs