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Biological and Medicinal Chemistry

Working Paper

Aryloxy Triester Phosphoramidates as Phosphoserine Biocleavable Masking Motifs

Ageo Miccoli, Binar A. Dhiani, Peter J. Thornton, Olivia A. Lambourne, Edward James, Hachemi Kadri, Youcef Mehellou

Version 1 posted 13 November 2019

496

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Biological and Medicinal Chemistry

Working Paper

Piperazine-fused cyclic disulfides: high-performance bioreduction-activated cores for bifunctional probes and reagents

Lukas Zeisel, Jan G. Felber, Karoline C. Scholzen, Carina Schmitt, Alexander J. Wiegand, Leonid Komissarov, Elias S. J. Arnér, Oliver Thorn-Seshold

Version 2 posted 10 October 2023

1,069

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Biological and Medicinal Chemistry

Working Paper

Bioorthogonal Regulation of Self-Immolation and Controlled Release Using Cucurbit[7]uril Supramolecular Chemistry

Xuancheng Fu, Bowen Xu, Suman Maity, Michelle Wu, Luke G. Westbrook, Katie Edwards, Atanu Acharya, Xiaoran Hu

Version 1 posted 03 October 2024

174

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Catalysis

Working Paper

Radiotherapy Mediated Catalytic Prodrug Therapy with Higher Radiochemical Conversion than Hydrated Electrons

Wei Cao, Jian Wang, Yin Liang, Sijie Wu, Ruotong Deng, Hanjie Zhu

Version 2 posted 25 April 2024

443

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Theoretical and Computational Chemistry

Working Paper

a coarse-grained molecular dynamics description of docetaxel-conjugate release from plga matrices

Martina Pannuzzo, Alessia Felici, Paolo Decuzzi

Version 1 posted 19 July 2022

182

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Biological and Medicinal Chemistry

Working Paper

A Photocaged Microtubule-Stabilising Epothilone allows Spatiotemporal Control of Cytoskeletal Dynamics

Carina Schmitt, Philipp Mauker, Nynke A. Vepřek, Carolin Gierse, Joyce C. M. Meiring, Jürgen Kuch, Anna Akhmanova, Leif Dehmelt, Oliver Thorn-Seshold

Version 1 posted 31 May 2024

292

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Biological and Medicinal Chemistry

Working Paper

3’-O-β-Glycosylation of nucleoside analogues using a promiscuous bacterial glycosyltransferase

Jonathan Dolan, Tessa Keenan, Caecilie Benckendorff, Aisling Ní Cheallaigh, Martin Fascione, Gavin Miller

Version 1 posted 16 May 2024

214

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Biological and Medicinal Chemistry

Working Paper

A Ligand-Directed Nitrophenol Carbonate for Transient In Situ Bioconjugation and Drug Delivery

Anthony J. Burt, Parvaneh Ahmadvand, Larissa K. Opp, ChulHee Kang, Rock Mancini

Version 2 posted 17 July 2020

732

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Biological and Medicinal Chemistry

Working Paper

A CNS-Targeting Prodrug Strategy for Nuclear Receptor Modulators

Skylar Ferrara, Thomas Scanlan

Version 1 posted 20 May 2020

1,059

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Organic Chemistry

Working Paper

Derivatisation of Parthenolide to Address Chemoresistant Chronic Lymphocytic Leukaemia

Xingjian Li, Daniel Payne, Badarinath Ampolu, Nicholas Bland, Jane T Brown, Mark Dutton, Catherine Fitton, Abigail Guliver, Lee Hale, Daniel Hamza, Geraint Jones, Rebecca Lane, Andrew Leach, Louise Male, Elena Merisor, Michael Morton, Alex Quy, Ruth Roberts, Rosanna Scarll, Timothy Schulz-Utermoehl, Tatjana Stankovic, Brett Stevenson, John Fossey, Angelo Agathanggelou

Version 1 posted 28 January 2019

923

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20 results in prodrug in Keywords: prodrug

Aryloxy Triester Phosphoramidates as Phosphoserine Biocleavable Masking Motifs

Piperazine-fused cyclic disulfides: high-performance bioreduction-activated cores for bifunctional probes and reagents

Bioorthogonal Regulation of Self-Immolation and Controlled Release Using Cucurbit[7]uril Supramolecular Chemistry

Radiotherapy Mediated Catalytic Prodrug Therapy with Higher Radiochemical Conversion than Hydrated Electrons

a coarse-grained molecular dynamics description of docetaxel-conjugate release from plga matrices

A Photocaged Microtubule-Stabilising Epothilone allows Spatiotemporal Control of Cytoskeletal Dynamics

3’-O-β-Glycosylation of nucleoside analogues using a promiscuous bacterial glycosyltransferase

A Ligand-Directed Nitrophenol Carbonate for Transient In Situ Bioconjugation and Drug Delivery

A CNS-Targeting Prodrug Strategy for Nuclear Receptor Modulators

Derivatisation of Parthenolide to Address Chemoresistant Chronic Lymphocytic Leukaemia

20 results in Keywords: prodrug