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Biological and Medicinal Chemistry

Working Paper

Epigenetics Recording Varied Environment and Complex Cell Events is an Origin of Cellular Aging

xuejun guo, Dong Yang, Xiangyuan Zhang

Version 1 posted 03 December 2018

360

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Biological and Medicinal Chemistry

Working Paper

Nitroreductase-Mediated Release of Inhibitors of Lysine-Specific Demethylase 1 (LSD1) from Prodrugs in Transfected Acute Myeloid Leukaemia Cells

Manfred Jung, Eva-Maria Herrlinger, Mirjam Hau, Desiree M. Redhaber, Gabriele Greve, Dominica Willmann, Simon Steimle, Michael Müller, Michael Lübbert, Cornelius Miething, Roland Schüle

Version 1 posted 24 October 2019

907

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Biological and Medicinal Chemistry

Working Paper

Epigenetic Target Prediction with Accurate Machine Learning Models

Norberto Sánchez-Cruz, Jose L. Medina-Franco

Version 1 posted 06 January 2021

437

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Biological and Medicinal Chemistry

Working Paper

Structure-Reactivity Relationships on Substrates and Inhibitors of the Lysine Deacylase Sirtuin 2 from Schistosoma Mansoni (SmSirt2)

Daria Monaldi, Dante Rotili, Julien Lancelot, Martin Marek, Nathalie Wössner, Alessia Lucidi, Daniela Tomaselli, Elizabeth Ramos-Morales, Christophe Romier, Raymond J. Pierce, Antonello Mai, Manfred Jung

Version 2 posted 02 August 2019

974

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Biological and Medicinal Chemistry

Working Paper

An Activity-based Probe Targeting Non-catalytic, Highly Conserved Amino Acid Residues Within Bromodomains

Melissa D’Ascenzio, Kathryn Pugh, Rebecca Konietzny, Georgina Berridge, Cynthia Tallant, Shaima Hashem, Octovia P. Monteiro, Jason R. Thomas, Markus Schirle, Stefan Knapp, Brian D. Marsden, Oleg Fedorov, Chas Bountra, Benedikt M. Kessler, Paul E. Brennan

Version 1 posted 17 October 2018

466

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Biological and Medicinal Chemistry

Working Paper

Epigenetic Target Profiler: A Web Server to Predict Epigenetic Targets of Small Molecules

Norberto Sánchez-Cruz, Jose L. Medina-Franco

Version 1 posted 07 January 2021

341

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Physical Chemistry

Working Paper

Photoinduced Intersystem Crossing in DNA Oxidative Lesions and Epigenetic Intermediates

Antonio Francés-Monerris, Mauricio Lineros-Rosa, Miguel Angél Miranda, Virginie Lhiaubet-Vallet, Antonio Monari

Version 1 posted 24 March 2020

316

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Biological and Medicinal Chemistry

Working Paper

Design, Synthesis and Characterization of Covalent KDM5 Inhibitors

Saleta Vazquez-Rodriguez, Miranda Wright, Catherine Rogers, Adam Cribbs, Srikannathasan Velupillai, Martin Philpott, Henry Lee, James E. Dunford, Kilian Huber, Matthew B. Robers, Jim Vasta, Marie-Laetitia Thezenas, Sarah Bonham, Benedikt M. Kessler, James Bennett, Oleg Fedorov, Florence Raynaud, Adam Donovan, Julian Blagg, Vassilios Bavetsias, Udo Oppermann, Akane Kawamura, Paul Brennan

Version 1 posted 11 September 2018

870

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Biological and Medicinal Chemistry

Working Paper

Hypoxia-Activated Pro-Drugs of the KDAC Inhibitor Vorinostat (SAHA)

Ewen D. D. Calder, Anna Skwarska, Ishna N. Mistry, Deborah Sneddon, Stuart Conway, Ester M. Hammond

Version 1 posted 16 October 2019

620

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1

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Biological and Medicinal Chemistry

Working Paper

Rapid Elaboration of Fragments into Leads Applied to Bromodomain-3 Extra Terminal Domain

Luke Adams, Lorna E. Wilkinson-White, Menachem J. Gunzburg, Stephen J. Headey, Martin J. Scanlon, Ben Capuano, Joel P. Mackay, Bradley Doak

Version 1 posted 25 March 2020

726

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Refine Search

36 results in epigenetics in Keywords: epigenetics

Epigenetics Recording Varied Environment and Complex Cell Events is an Origin of Cellular Aging

Nitroreductase-Mediated Release of Inhibitors of Lysine-Specific Demethylase 1 (LSD1) from Prodrugs in Transfected Acute Myeloid Leukaemia Cells

Epigenetic Target Prediction with Accurate Machine Learning Models

Structure-Reactivity Relationships on Substrates and Inhibitors of the Lysine Deacylase Sirtuin 2 from Schistosoma Mansoni (SmSirt2)

An Activity-based Probe Targeting Non-catalytic, Highly Conserved Amino Acid Residues Within Bromodomains

Epigenetic Target Profiler: A Web Server to Predict Epigenetic Targets of Small Molecules

Photoinduced Intersystem Crossing in DNA Oxidative Lesions and Epigenetic Intermediates

Design, Synthesis and Characterization of Covalent KDM5 Inhibitors

Hypoxia-Activated Pro-Drugs of the KDAC Inhibitor Vorinostat (SAHA)

Rapid Elaboration of Fragments into Leads Applied to Bromodomain-3 Extra Terminal Domain

36 results in Keywords: epigenetics