Search

Synthesis of All-carbon Disubstituted Bicyclo[1.1.1]pentanes by Iron-Catalyzed Kumada CrossCoupling

Jeremy Nugent, Bethany Shire, Dimitri F. J. Caputo, Helena D. Pickford, Frank Nightingale, Ian T. T. Houlsby, James J. Mousseau, Edward Anderson

Version 1 posted 20 March 2020

961

Downloads

Organic Chemistry

Working Paper

Synthesis of Highly Enantioenriched Sulfonimidoyl Fluorides and Sulfonimidamides by Stereospecific SuFEx Reaction

Stephanie Greed, Edward L. Briggs, Fahima Idiris, Andrew J. P. White, Ulrich Lücking, James Bull

Version 1 posted 06 May 2020

728

Downloads

Organic Chemistry

Working Paper

Investigation of the Reactivity of 1-Azido-3-Iodobicyclo[1.1.1]pentane under “Click” Reaction Conditions

Elisabeth Sitte, Brendan Twamley, nitika grover, Mathias O.. Senge

Version 1 posted 12 October 2020

485

Downloads

Organic Chemistry

Working Paper

General access to cubanes: ideal bioisosteres of ortho-, meta-, and para-substituted benzenes

Mario P. Wiesenfeldt, James. A. Rossi-Ashton, Ian B. Perry, Johannes Diesel, Olivia L. Garry, Florian Bartels, Susannah C. Coote, Xiaoshen Ma, Charles S. Yeung, David Jonathan Bennett, David W. C. MacMillan

Version 1 posted 23 January 2023

5,030

Downloads

1

Citations

Organic Chemistry

Working Paper

Stellane at the Forefront: Derivatization and Reactivity Studies of a Promising Saturated Bioisostere of ortho‐Substituted Benzenes

Oleh Smyrnov, Kostiantyn Melnykov, Olexandr Pashenko, Dmytro Volochnyuk, Serhiy Ryabukhin

Version 1 posted 18 January 2024

323

Downloads

1

Citations

Organic Chemistry

Working Paper

C−F Bond Activation Enables Synthesis of Aryl Difluoromethyl Bicyclopentanes as Benzophenone-Type Bioisosteres

Mingshuo Chen, Yuang Cui, Xiaoping Chen, Rui Shang, Xiaheng Zhang

Version 1 posted 22 August 2023

1,503

Downloads

3

Citations

Biological and Medicinal Chemistry

Working Paper

More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-a]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication

Han Wee Ong, Xuan Yang, Jeffery Smith, Rebekah Dickmander, Jason Brown, Tammy Havener, Sharon Taft-Benz, Stefanie Howell, Marcia Sanders, Jacob Capener, Rafael Couñago, Edcon Chang, Andreas Krämer, Nathaniel Moorman, Mark Heise, Alison Axtman, David Drewry, Timothy Willson

Version 1 posted 24 April 2024

199

Downloads

Organic Chemistry

Working Paper

Selective Synthesis of 1,3-Substituted Cuneanes: En Route to Potent Bioisosteres of m-Substituted Benzenes

Shota Nagasawa, Kan Fujiwara, Ryusei Maeyama, Ryosuke Segawa, Noriyasu Hirasawa, Takatsugu Hirokawa, Yoshiharu Iwabuchi

Version 2 posted 26 July 2023

1,015

Downloads

1

Citations

Biological and Medicinal Chemistry

Working Paper

Bioisostere-conjugated fluorescent probes for live-cell protein imaging without non-specific organelle accumulation.

Takuya Kamikawa, Akari Hashimoto, Nozomi Yamazaki, Junya Adachi, Kazuya Kikuchi, Yuichiro Hori

Version 2 posted 29 December 2023

449

Downloads

Organic Chemistry

Working Paper

1,2-Difunctionalized Bicyclo[1.1.1]pentanes: Long Sought After Bioisosteres for ortho/meta-Substituted Arenes

Jin-Xin Zhao, Yuxuan Chang, Jeff Elleraas, T. Patrick Montgomery,, Jillian E. Spangler, Sajiv K. Nair, Matthew Del Bel, Gary M. Gallego, James J. Mousseau, Matthew A. Perry, Michael R. Collins, Julien Vantourout, Phil Baran

Version 1 posted 21 October 2020

3,801

Downloads

5

Citations

Refine Search

21 results in bioisostere in Keywords: bioisostere

Synthesis of All-carbon Disubstituted Bicyclo[1.1.1]pentanes by Iron-Catalyzed Kumada CrossCoupling

Synthesis of Highly Enantioenriched Sulfonimidoyl Fluorides and Sulfonimidamides by Stereospecific SuFEx Reaction

Investigation of the Reactivity of 1-Azido-3-Iodobicyclo[1.1.1]pentane under “Click” Reaction Conditions

General access to cubanes: ideal bioisosteres of ortho-, meta-, and para-substituted benzenes

Stellane at the Forefront: Derivatization and Reactivity Studies of a Promising Saturated Bioisostere of ortho‐Substituted Benzenes

C−F Bond Activation Enables Synthesis of Aryl Difluoromethyl Bicyclopentanes as Benzophenone-Type Bioisosteres

More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-a]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication

Selective Synthesis of 1,3-Substituted Cuneanes: En Route to Potent Bioisosteres of m-Substituted Benzenes

Bioisostere-conjugated fluorescent probes for live-cell protein imaging without non-specific organelle accumulation.

1,2-Difunctionalized Bicyclo[1.1.1]pentanes: Long Sought After Bioisosteres for ortho/meta-Substituted Arenes

21 results in Keywords: bioisostere