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Targeted Quantification of Proteoforms in Complex Samples by Proteoform Reaction Monitoring

Che-Fan Huang, Jake Kline, Fernanda Negrão, Matthew Robey, Timothy Toby, Kenneth Durbin, Ryan Fellers, John Friedewald, Josh Levitsky, Michael Abecassis, Rafael Melani, Neil Kelleher, Luca Fornelli

Version 1 posted 27 June 2023

389

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1

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Analytical Chemistry

Working Paper

PEPPI-MS: Strategies to Enhance the Extraction of Electrophoretically Separated Proteins from Polyacrylamide Gels and Their Application to Top-Down/native Mass Spectrometry

Ayako Takemori, Lissa C Anderson, Victoria M. Harman, Philip Brownridge, David Butcher, Keisuke Shima, Daisuke Higo, Jun Ishizaki, Hitoshi Hasegawa, Junpei Suzuki, Masakatsu Yamashita, Joseph A. Loo, Rachel R. Ogorzalek Loo, Robert J. Beynon, Nobuaki Takemori

Version 1 posted 01 October 2019

634

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Analytical Chemistry

Working Paper

Comparing Top-Down Proteoform Identification: Deconvolution, PrSM Overlap, and PTM Detection

David Tabb, Kyowon Jeong, Karen Druart, Megan Gant, Kyle Brown, Carrie Nicora, Mowei Zhou, The Milk Microbiome and Metabolome, Julia Chamot-Rooke

Version 1 posted 22 December 2022

359

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Analytical Chemistry

Working Paper

Sequential Ion-Ion Reactions for Enhanced Gas-Phase Sequencing of Large Intact Proteins in a Tribrid Orbitrap Mass Spectrometer

Jake Kline, Christopher Mullen, Kenneth Durbin, Ryan Oates, Romain Huguet, John Syka, Luca Fornelli

Version 1 posted 17 February 2021

532

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Analytical Chemistry

Working Paper

Internal Fragments Generated by Electron Ionization Dissociation Enhances Protein Top-down Mass Spectrometry

Muhammad Zenaidee, Carter Lantz, Taylor Perkins, Janine Fu, Wonhyuek Jung, Rachel R. Ogorzalek Loo, Joseph A. Loo

Version 2 posted 27 February 2020

1,030

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Analytical Chemistry

Working Paper

Spatially resolved top-down proteomics of tissue sections based on a microfluidic nanodroplet sample preparation platform

Yen-Chen Liao, James Fulcher, David Degnan, Sarah Williams, Lisa Bramer, Dušan Veličković, Kevin Zemaitis, Marija Veličković, Ryan Sontag, Ronald Moore, Ljiljana Paša-Tolić, Ying Zhu, Mowei Zhou

Version 2 posted 22 December 2022

529

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Analytical Chemistry

Working Paper

Mapping the Proteoform Landscape of Five Human Tissues

Bryon Drown, Kevin Jooß, Rafael Melani, Cameron Lloyd-Jones, Jeannie Camarillo, Neil Kelleher

Version 1 posted 19 January 2022

344

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Analytical Chemistry

Working Paper

193 nm ultraviolet photodissociation for the characterization of singly charged proteoforms generated by MALDI

Kevin Zemaitis, Mowei Zhou, William Kew, Ljiljana Paša-Tolić

Version 2 posted 06 January 2023

255

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Analytical Chemistry

Working Paper

De Novo Sequencing of Antibody Light Chain Proteoforms from Patients with Multiple Myeloma

Mathieu Dupré, Magalie Duchateau, Rebecca Sternke-Hoffmann, Amelie Boquoi, Christian Malosse, Roland Fenk, Rainer Haas, Alexander Buell, Martial Rey, Julia Chamot-Rooke

Version 1 posted 07 May 2021

362

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Analytical Chemistry

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Top-Down Analysis of Supercharged Proteins Using Collision-, Electron-, and Photon-Based Activation Methods

Kyle Juetten, Jennifer Brodbelt

Version 1 posted 17 April 2023

193

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11 results in Top-down proteomics in Keywords: Top-down proteomics

Targeted Quantification of Proteoforms in Complex Samples by Proteoform Reaction Monitoring

PEPPI-MS: Strategies to Enhance the Extraction of Electrophoretically Separated Proteins from Polyacrylamide Gels and Their Application to Top-Down/native Mass Spectrometry

Comparing Top-Down Proteoform Identification: Deconvolution, PrSM Overlap, and PTM Detection

Sequential Ion-Ion Reactions for Enhanced Gas-Phase Sequencing of Large Intact Proteins in a Tribrid Orbitrap Mass Spectrometer

Internal Fragments Generated by Electron Ionization Dissociation Enhances Protein Top-down Mass Spectrometry

Spatially resolved top-down proteomics of tissue sections based on a microfluidic nanodroplet sample preparation platform

Mapping the Proteoform Landscape of Five Human Tissues

193 nm ultraviolet photodissociation for the characterization of singly charged proteoforms generated by MALDI

De Novo Sequencing of Antibody Light Chain Proteoforms from Patients with Multiple Myeloma

Top-Down Analysis of Supercharged Proteins Using Collision-, Electron-, and Photon-Based Activation Methods

11 results in Keywords: Top-down proteomics