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Abstract
We are submitting a manuscript describing the application of proton transfer charge reduction to increase the sequence coverage for proteins > 30 kDa using Orbitrap FTMS.
Sequential Ion-Ion Reactions for Enhanced Gas-Phase Sequencing of Large Intact Proteins in a Tribrid Orbitrap Mass Spectrometer
17 February 2021, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.
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Version History
Feb 17, 2021 Version 1
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Author’s competing interest statement
C.M., J.E.P.S. and R.H. are employees of Thermo Scientific. K.R.D. is an employee of Proteinaceous, which commercializes software for the analysis of top-down mass spectrometry data.