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PROTAC degraders of the METTL3-14 m6A-RNA methyltransferase

Francesco Errani, Annalisa Invernizzi, Marcin Herok, Elena Bochenkova, Fiona Stamm, Ivan Corbeski, Valeria Romanucci, Giovanni Di Fabio, František Zálešák, Amedeo Caflisch

Version 2 posted 06 February 2024

723

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Organic Chemistry

Working Paper

An Integrated Direct-to-Biology Platform for the Nanoscale Synthesis and Biological Evaluation of PROTACs

Rebecca Stevens, Enrique Bendito-Moll, David Battersby, Afjal Miah, Natalie Wellaway, Robert Law, Peter Stacey, Diana Klimaszewska, Justyna Macina, Glenn Burley, John Harling

Version 2 posted 01 September 2023

2,226

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1

Citations

Biological and Medicinal Chemistry

Working Paper

Ternary Complex-Templated Dynamic Combinatorial Chemistry for the Selection and Identification of Homo-PROTACs

Claudia Diehl, Alessandra Salerno, Alessio Ciulli

Version 2 posted 09 April 2024

1,329

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Biological and Medicinal Chemistry

Working Paper

Efficient targeted degradation via reversible and irreversible covalent PROTACs

Ronen Gabizon, Amit Shraga, Paul Gehrtz, Ella Livnah, Yamit Shorer, Neta Gurwicz, Liat Avram, Tamar Unger, Hila Aharoni, Shira Albeck, Alexander Brandis, Ziv Shulman, Ben- Zion Katz, Yair Herishanu, Nir London

Version 2 posted 17 March 2020

2,481

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Biological and Medicinal Chemistry

Working Paper

Development of a Hematopoietic Prostaglandin D Synthase-Degradation Inducer

Hidetomo Yokoo, Norihito Shibata, Miyako Naganuma, Kiyonaga Fujii, Takahito Ito, Kosuke Aritake, Mikihiko Naito, Yosuke Demizu

Version 1 posted 05 October 2020

521

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Biological and Medicinal Chemistry

Working Paper

Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs

Christian Steinebach, Izidor Sosič, Aleša Bricelj, Arunima Murgai, Luca Bischof, Yuen Lam Dora Ng, Christopher Heim, Samuel Maiwald, Matic Proj, Rabea Voget, Felix Feller, Janez Košmrlj, Annika Schmidt, Patricia Lemnitzer, Finn K. Hansen, Michael Gütschow, Jan Krönke, Marcus D. Hartmann

Version 1 posted 21 April 2023

1,597

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1

Citations

Biological and Medicinal Chemistry

Working Paper

Expanding the PROTAC Toolbox: Targeted Degradation of the Deubiquitinase USP7 in Cancer

Arunima Murgai, Izidor Sosič, Martina Gobec, Patricia Lemnitzer, Matic Proj, Sophie Wittenburg, Michael Gütschow, Jan Krönke, Christian Steinebach

Version 1 posted 13 April 2022

1,274

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Biological and Medicinal Chemistry

Working Paper

Structure-Based Design of a Macrocyclic PROTAC

Andrea Testa, Scott J. Hughes, Xavier Lucas, Jane E. Wright, Alessio Ciulli

Version 2 posted 20 November 2019

2,281

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Biological and Medicinal Chemistry

Working Paper

A comprehensive kinetic model for ternary complex catalysis

Eugene F. Douglass Jr., Chad J. Miller

Version 2 posted 27 January 2022

1,395

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2

Citations

Catalysis

Working Paper

Ruthenium-catalysed C‒H amidation for the late-stage synthesis of PROTACs

Daniele Antermite, Stig D. Friis, Johan R. Johansson, Okky D. Putra, Lutz Ackermann, Magnus J. Johansson

Version 1 posted 27 March 2023

1,073

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Refine Search

19 results in PROTACs in Keywords: PROTACs

PROTAC degraders of the METTL3-14 m6A-RNA methyltransferase

An Integrated Direct-to-Biology Platform for the Nanoscale Synthesis and Biological Evaluation of PROTACs

Ternary Complex-Templated Dynamic Combinatorial Chemistry for the Selection and Identification of Homo-PROTACs

Efficient targeted degradation via reversible and irreversible covalent PROTACs

Development of a Hematopoietic Prostaglandin D Synthase-Degradation Inducer

Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs

Expanding the PROTAC Toolbox: Targeted Degradation of the Deubiquitinase USP7 in Cancer

Structure-Based Design of a Macrocyclic PROTAC

A comprehensive kinetic model for ternary complex catalysis

Ruthenium-catalysed C‒H amidation for the late-stage synthesis of PROTACs

19 results in Keywords: PROTACs