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Biological and Medicinal Chemistry

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Nitroreductase

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5 results in Keywords: Nitroreductase

Biological and Medicinal Chemistry

Nitroreductase-Mediated Release of Inhibitors of Lysine-Specific Demethylase 1 (LSD1) from Prodrugs in Transfected Acute Myeloid Leukaemia Cells

Manfred Jung, Eva-Maria Herrlinger, Mirjam Hau, Desiree M. Redhaber, Gabriele Greve, Dominica Willmann, Simon Steimle, Michael Müller, Michael Lübbert, Cornelius Miething, Roland Schüle

Version 1 posted 24 October 2019

950

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Organic Chemistry

Novel Water-Soluble Far-Red Nitroreductase-Responsive Bodipy-Based Fluorescent Probe for the Detection of Hypoxic Status in A549 Non-Small Cell Lung Cancer Cells

Sergey A. GORBATOV, Denis Y. UVAROV, Alexander M. SCHERBAKOV, Igor V. ZAVARZIN, Yulia A. VOLKOVA, Anthony ROMIEU

Version 1 posted 03 July 2020

422

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1

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Biological and Medicinal Chemistry

Hydrolysis-resistant ester-based linkers enable ABS probe development for NIR bioluminescent imaging of hypoxia

Anuj Yadav, Zhenxiang Zhao, Yourong Weng, Sarah Gardner, Catharine Brady, Oliver Pichardo Peguero, Jefferson Chan

Version 1 posted 01 November 2022

412

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Biological and Medicinal Chemistry

An activatable biphotonic lanthanide probe for detection of nitroreductase in live bacteria and cancer cells

Carolina Vinagreiro, Qian Liu, Qinghua Wang, Xiang Wang, Hai-Yu Hu, Marc Nazare

Version 1 posted 05 February 2024

215

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Accessing active fragments for drug discovery utilising nitroreductase biocatalysis

Lauren Holder, Eda Yuce, Gabriel Oriomah, Aimee Jenkins, Jóhannes Reynisson, Anja Winter, Sebastian Cosgrove

Version 1 posted 12 March 2024

304

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