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Biological and Medicinal Chemistry

Working Paper

Traceless Click-Assisted Native Chemical Ligation Enabled by Protecting Dibenzocyclooctyne from Acid-Mediated Rearrangement with Copper(I)

Patrick Erickson, James Fulcher, Michael Kay

Version 1 posted 13 July 2020

1,104

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Organic Chemistry

Working Paper

A selenium-based cysteine surrogate for protein chemical synthesis

Olga Firstova, Vangelis Agouridas, Vincent Diemer, Oleg Melnyk

Version 1 posted 16 September 2021

380

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Biological and Medicinal Chemistry

Working Paper

BracketMaker: Visualization and Optimization of Chemical Protein Synthesis

Judah Evangelista, Michael S. Kay

Version 1 posted 29 May 2024

128

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Biological and Medicinal Chemistry

Working Paper

Rapid building block-economic synthesis of long, multi-O-GalNAcylated MUC5AC tandem repeat peptides

Arseniy Galashov, Ekaterina Kazakova, Christian Stieger, Christian Hackenberger, Oliver Seitz

Version 1 posted 18 September 2023

318

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Biological and Medicinal Chemistry

Working Paper

Rapid Production of Native and Mirror-Image Tumor Necrosis Factor-α through the Synergy of Automated Flow Peptide Synthesis and Native Chemical Ligation

Ahmet Yesilcimen, Alex J. Callahan, Tara L. Travaline, Satish Gandhesiri, Olena S. Tokareva, Andrei Loas, John H. McGee, Bradley L. Pentelute

Version 1 posted 02 February 2024

410

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Biological and Medicinal Chemistry

Working Paper

Copper-mediated selenazolidine deprotection enables one-pot chemical synthesis of challenging proteins

Zhenguang Zhao, Norman Metanis

Version 1 posted 23 July 2019

856

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Biological and Medicinal Chemistry

Working Paper

Diselenide Crosslinks for Enhanced and Simplified Oxidative Protein Folding

Reem Mousa, Taghreed Hidmi, Sergei Pomyalov, Shifra Lansky, Lareen Khouri, Deborah E. Shalev, Gil Shoham, Norman Metanis

Version 1 posted 07 August 2020

346

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Biological and Medicinal Chemistry

Working Paper

Chemical Synthesis of Shiga Toxin Subunit B Using a Next-Generation Traceless “Helping Hand” Solubilizing Tag

James Fulcher, Mark Petersen, riley giesler, Zachary Cruz, debra eckert, J. Nicholas Francis, eric kawamoto, Michael Jacobsen, Michael Kay

Version 2 posted 23 September 2019

809

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Biological and Medicinal Chemistry

Working Paper

A Straightforward Methodology to Overcome Solubility Challenges for N-Terminal Cysteinyl Peptide Segments Used in Native Chemical Ligation

Skander Abboud, El hadji Cisse, Michel Doudeau, Hélène Bénédetti, Vincent AUCAGNE

Version 1 posted 03 November 2020

421

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Organic Chemistry

Working Paper

Utilizing Copper-Mediated Deprotection of Selenazolidine for Cyclic Peptides Synthesis

Zhenguang Zhao, Norman Metanis

Version 1 posted 01 October 2019

796

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Refine Search

25 results in Native Chemical Ligation in Keywords: Native Chemical Ligation

Traceless Click-Assisted Native Chemical Ligation Enabled by Protecting Dibenzocyclooctyne from Acid-Mediated Rearrangement with Copper(I)

A selenium-based cysteine surrogate for protein chemical synthesis

BracketMaker: Visualization and Optimization of Chemical Protein Synthesis

Rapid building block-economic synthesis of long, multi-O-GalNAcylated MUC5AC tandem repeat peptides

Rapid Production of Native and Mirror-Image Tumor Necrosis Factor-α through the Synergy of Automated Flow Peptide Synthesis and Native Chemical Ligation

Copper-mediated selenazolidine deprotection enables one-pot chemical synthesis of challenging proteins

Diselenide Crosslinks for Enhanced and Simplified Oxidative Protein Folding

Chemical Synthesis of Shiga Toxin Subunit B Using a Next-Generation Traceless “Helping Hand” Solubilizing Tag

A Straightforward Methodology to Overcome Solubility Challenges for N-Terminal Cysteinyl Peptide Segments Used in Native Chemical Ligation

Utilizing Copper-Mediated Deprotection of Selenazolidine for Cyclic Peptides Synthesis

25 results in Keywords: Native Chemical Ligation