Search

Directed Evolution of P450 Fatty Acid Decarboxylases via High-Throughput Screening Towards Improved Catalytic Activity

Huifang Xu, Weinan Liang, Linlin Ning, Yuanyuan Jiang, Wenxia Yang, Cong Wang, Feifei Qi, Li Ma, Lei Du, Laurent Fourage, Yongjin J. Zhou, Shengying Li

Version 1 posted 11 September 2019

719

Downloads

Catalysis

Working Paper

Origin and Control of Chemoselectivity in Cytochrome c-Catalyzed Carbene Transfer into Si–H and N–H bonds

Marc Garcia-Borràs, S. B. Jennifer Kan, Russell D. Lewis, Allison Tang, Gonzalo Jiménez-Osés, Frances H. Arnold, Kendall N. Houk

Version 1 posted 25 February 2021

468

Downloads

Catalysis

Working Paper

Tailoring Tryptophan Synthase TrpB for Selective Quaternary Carbon Bond Formation

Markus Dick, Nicholas S. Sarai, Michael W. Martynowycz, Tamir Gonen, Frances H. Arnold

Version 1 posted 12 September 2019

934

Downloads

Catalysis

Working Paper

Diverse engineered heme proteins enable stereodivergent cyclopropanation of unactivated alkenes

Anders M. Knight, S. B. Jennifer Kan, Russell D. Lewis, Oliver F. Brandenberg, Kai Chen, Frances H. Arnold

Version 1 posted 20 December 2017

1,214

Downloads

Biological and Medicinal Chemistry

Working Paper

Straightforward Background Depletion Unlocks Transaminase Evolution Through Solid-Phase Screening

Matteo Planchestainer, Eimear Hegarty, Christian Heckmann, Louise Gourlay, Francesca Paradisi

Version 1 posted 25 March 2019

526

Downloads

Catalysis

Working Paper

Flavin-Dependent Halogenases Catalyze Enantioselective Olefin Halocyclization

Dibyendu Mondal, Brian F. Fisher, Yuhua Jiang, Jared C. Lewis

Version 1 posted 22 September 2020

771

Downloads

1

Citations

Biological and Medicinal Chemistry

Working Paper

Engineered Biosynthesis of β-Alkyl Tryptophan Analogs

Christina E. Boville, Remkes A. Scheele, Philipp Koch, Sabine Brinkmann-Chen, Andrew R. Buller, Frances H. Arnold

Version 1 posted 13 July 2018

738

Downloads

Biological and Medicinal Chemistry

Working Paper

An Engineered Nonribosomal Peptide Synthetase Shows Opposite Amino Acid Loading and Condensation Specificity

Aleksa Stanišić, Annika Hüsken, Philipp Stephan, David L. Niquille, Jochen Reinstein, Hajo Kries

Version 1 posted 16 March 2021

872

Downloads

Catalysis

Working Paper

Biocatalytic Conversion of 5-Hydroxymethylfurfural by Galactose Oxidase: Toward Scalable Technology Using Integrated Process and Enzyme Engineering

William Birmingham, Asbjørn Toftgaard Pedersen, Mafalda Dias Gomes, Mathias Bøje Madsen, Michael Breuer, John Woodley, Nicholas J. Turner

Version 1 posted 08 September 2020

608

Downloads

2

Citations

Biological and Medicinal Chemistry

Working Paper

Nitrene Transfer Catalyzed by a Non-Heme Iron Enzyme and Enhanced by Non-Native Small-Molecule Cofactors

Nathaniel Goldberg, Anders M. Knight, Ruijie Zhang, Frances H. Arnold

Version 1 posted 05 November 2019

1,183

Downloads

Refine Search

45 results in Directed Evolution in Keywords: Directed Evolution

Directed Evolution of P450 Fatty Acid Decarboxylases via High-Throughput Screening Towards Improved Catalytic Activity

Origin and Control of Chemoselectivity in Cytochrome c-Catalyzed Carbene Transfer into Si–H and N–H bonds

Tailoring Tryptophan Synthase TrpB for Selective Quaternary Carbon Bond Formation

Diverse engineered heme proteins enable stereodivergent cyclopropanation of unactivated alkenes

Straightforward Background Depletion Unlocks Transaminase Evolution Through Solid-Phase Screening

Flavin-Dependent Halogenases Catalyze Enantioselective Olefin Halocyclization

Engineered Biosynthesis of β-Alkyl Tryptophan Analogs

An Engineered Nonribosomal Peptide Synthetase Shows Opposite Amino Acid Loading and Condensation Specificity

Biocatalytic Conversion of 5-Hydroxymethylfurfural by Galactose Oxidase: Toward Scalable Technology Using Integrated Process and Enzyme Engineering

Nitrene Transfer Catalyzed by a Non-Heme Iron Enzyme and Enhanced by Non-Native Small-Molecule Cofactors

45 results in Keywords: Directed Evolution