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Highly Selective Novel Heme Oxygenase-1-Targeting Molecules Discovered by DNA-Encoded Library-Machine Learning Model beyond the DEL Chemical Space

Shuai Han, Xinyun Guo, Min Wang, Huan Liu, Yidan Song, Yunyun He, Kuang-Lung Hsueh, Weiren Cui, Wenji Su, Letian Kuai, Jason Deng

Version 1 posted 07 March 2024

332

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Organic Chemistry

Working Paper

Exploiting Chemical Diversity through C–H Activation and DNA-Encoding

Zhoulong Fan, Shuai Zhao, Tao Liu, Peng-Xiang Shen, Zi-Ning Cui, Zhe Zhuang, Qian Shao, Jason Chen, Anokha S. Ratnayake, Mark E. Flanagan, Dominik K. Kölmel, David W. Piotrowski, Paul Richardson, jin-quan yu

Version 1 posted 08 January 2020

1,329

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2

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Analytical Chemistry

Working Paper

Antibody-Inspired Affinity Measurements of Fluorescein-Linked Small Molecule Ligands

Marco Catalano, Sebastian Oehler, Luca Prati, Nicholas Favalli, Gabriele Bassi, Jörg Scheuermann, Dario Neri

Version 1 posted 29 May 2020

657

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Organic Chemistry

Working Paper

Water-Compatible Cycloadditions of Oligonucleotide-Conjugated Strained Allenes for DNA-Encoded Library Synthesis

Matthias V. Westphal, Liam Hudson, Jeremy W. Mason, Frédéric J. Zécri, Karin Briner, Stuart L. Schreiber

Version 1 posted 17 December 2019

761

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Biological and Medicinal Chemistry

Working Paper

A method to identify small molecule/protein pairs susceptible to protein ubiquitination

Pinwen Cai, Basilius Sauter, Saule Zhanybekova, Dennis Gillingham

Version 1 posted 22 April 2024

353

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Organic Chemistry

Working Paper

A Machine-learning-based Data Analysis Method for Cell-based Selection of DNA-encoded libraries (DELs)

Rui Hou, Chao Xie, Yuhan Gui, Gang Li, Xiaoyu Li

Version 1 posted 30 September 2022

897

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1

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Biological and Medicinal Chemistry

Working Paper

Photoredox-catalysed Hydroaminoalkylation of on-DNA N- Arylamines

Yasaman Mahdavi-Amiri, Nicole Frias, Adam Csakai, Lisa Marcaurelle, Ryan Hili

Version 1 posted 27 October 2022

443

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Biological and Medicinal Chemistry

Working Paper

DNA Barcoding a Complete Matrix of Stereoisomeric Small Molecules

Christopher Gerry, Mathias Wawer, Paul Clemons, Stuart Schreiber

Version 3 posted 22 April 2019

2,118

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Organic Chemistry

Working Paper

Synthesis and Screening of A DNA-Encoded Library of Non-Peptidic Macrocycles

Eric Koesema, Animesh Roy, Nicholas G. Paciaroni, Thomas Kodadek

Version 1 posted 29 December 2020

723

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2

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Biological and Medicinal Chemistry

Working Paper

Selection of DNA-encoded Chemical Libraries for Compounds that can Induce Protein Ubiquitination

Cen Huang, Xingyuan Liu, Xinyuan Wu, Ling Meng, Xiaojie Lu, Xiaoyu Li

Version 1 posted 12 February 2024

824

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11 results in DNA-Encoded library in Keywords: DNA-Encoded library

Highly Selective Novel Heme Oxygenase-1-Targeting Molecules Discovered by DNA-Encoded Library-Machine Learning Model beyond the DEL Chemical Space

Exploiting Chemical Diversity through C–H Activation and DNA-Encoding

Antibody-Inspired Affinity Measurements of Fluorescein-Linked Small Molecule Ligands

Water-Compatible Cycloadditions of Oligonucleotide-Conjugated Strained Allenes for DNA-Encoded Library Synthesis

A method to identify small molecule/protein pairs susceptible to protein ubiquitination

A Machine-learning-based Data Analysis Method for Cell-based Selection of DNA-encoded libraries (DELs)

Photoredox-catalysed Hydroaminoalkylation of on-DNA N- Arylamines

DNA Barcoding a Complete Matrix of Stereoisomeric Small Molecules

Synthesis and Screening of A DNA-Encoded Library of Non-Peptidic Macrocycles

Selection of DNA-encoded Chemical Libraries for Compounds that can Induce Protein Ubiquitination

11 results in Keywords: DNA-Encoded library