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Biological and Medicinal Chemistry

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Monodisperse Polysarcosine-based Highly-loaded Antibody-Drug Conjugates

Warren Viricel, Guy Fournet, Sabine Beaumel, Emeline Perrial, Sébastien Papot, Charles Dumontet, Benoît Joseph

Version 2 posted 17 December 2018

1,065

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Organic Chemistry

Working Paper

Gram-Scale Synthesis of Site-Specific Antibody-Drug Conjugates Using AJICAP Second-Generation Technology

Tomohiro Watanabe, Tomohiro Fujii, Jason Stofleth, Rika Takasugi, Kazutoshi Takahashi, Yutaka Matsuda

Version 1 posted 05 April 2023

582

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2

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Biological and Medicinal Chemistry

Working Paper

AJICAP Second Generation: Improved Chemical Site-Specific Conjugation Technology for Antibody-Drug Conjugate Production

Tomohiro Fujii, Yutaka Matsuda, Takuya Seki, Natsuki Shikida, Yusuke Iwai, Yuri Ooba, Kazutoshi Takahashi, Muneki Isokawa, Sayaka Kawaguchi, Noriko Hatada, Tomohiro Watanabe, Rika Takasugi, Akira Nakayama, Kazutaka Shimbo, Brian. A. Mendelsohn, Tatsuya Okuzumi, Kei Yamada

Version 1 posted 31 January 2023

887

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2

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Analytical Chemistry

Working Paper

The UniDec Processing Pipeline for Rapid Analysis of Biotherapeutic Mass Spectrometry Data

Wilson Phung, Corey Bakalarski, Trent Hinkle, Wendy Sandoval, Michael Marty

Version 2 posted 03 July 2023

740

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Biological and Medicinal Chemistry

Working Paper

Galactose Oxidase Enables Modular Assembly of Conjugates from Native Antibodies with High Drug-to-Antibody Ratios

Antonio Angelastro, Alexey Barkhanskiy, Ashley P. Mattey, Edward G. Pallister, Reynard Spiess, William Goundry, Perdita Barran, Sabine L. Flitsch

Version 1 posted 06 December 2021

322

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Biological and Medicinal Chemistry

Working Paper

Bispecific Antibodies Produced via Chemical Site-Specific Conjugation Technology: AJICAP Second Generation

Tomohiro Fujii, Kenichiro Ito, Kazutoshi Takahashi, Tsubasa Aoki, Takuya Seki, Yusuke Iwai, Rika Takasugi, Tomohiro Watanabe, Ryusuke Hirama, Ryo Tsumura, Hirobumi Fuchigami, Masahiro Yasunaga, Yutaka Matsuda

Version 1 posted 25 August 2023

330

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Organic Chemistry

Working Paper

AJICAP-M: Traceless Affinity Peptide Mediated Conjugation Technology for Site-Specific Antibody-Drug Conjugate Synthesis

Yutaka Matsuda, Natsuki Shikida, Noriko Hatada, Kei Yamada, Takuya Seki, Yuichi Nakahara, Yuta Endo, Kazutaka Shimbo, Kazutoshi Takahashi, Akira Nakayama, Brian A. Mendelsohn, Tomohiro Fujii, Tatsuya Okuzumi, Shigeo Hirasawa

Version 1 posted 12 March 2024

622

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1

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Organic Chemistry

Working Paper

Enhanced Chemical Method for Bispecific Antibody Production: Leveraging Site-Specific Conjugation and Stable Crosslinker Technology

Tomohiro Fujii, Yutaka Matsuda

Version 1 posted 20 November 2024

0

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8 results in Antibody-drug Conjugates in Keywords: Antibody-drug Conjugates

Monodisperse Polysarcosine-based Highly-loaded Antibody-Drug Conjugates

Gram-Scale Synthesis of Site-Specific Antibody-Drug Conjugates Using AJICAP Second-Generation Technology

AJICAP Second Generation: Improved Chemical Site-Specific Conjugation Technology for Antibody-Drug Conjugate Production

The UniDec Processing Pipeline for Rapid Analysis of Biotherapeutic Mass Spectrometry Data

Galactose Oxidase Enables Modular Assembly of Conjugates from Native Antibodies with High Drug-to-Antibody Ratios

Bispecific Antibodies Produced via Chemical Site-Specific Conjugation Technology: AJICAP Second Generation

AJICAP-M: Traceless Affinity Peptide Mediated Conjugation Technology for Site-Specific Antibody-Drug Conjugate Synthesis

Enhanced Chemical Method for Bispecific Antibody Production: Leveraging Site-Specific Conjugation and Stable Crosslinker Technology

8 results in Keywords: Antibody-drug Conjugates