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Biological and Medicinal Chemistry

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Organic Chemistry

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AJICAP

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5 results in Keywords: AJICAP

Organic Chemistry

Gram-Scale Synthesis of Site-Specific Antibody-Drug Conjugates Using AJICAP Second-Generation Technology

Tomohiro Watanabe, Tomohiro Fujii, Jason Stofleth, Rika Takasugi, Kazutoshi Takahashi, Yutaka Matsuda

Version 1 posted 05 April 2023

582

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2

Citations

Biological and Medicinal Chemistry

AJICAP Second Generation: Improved Chemical Site-Specific Conjugation Technology for Antibody-Drug Conjugate Production

Tomohiro Fujii, Yutaka Matsuda, Takuya Seki, Natsuki Shikida, Yusuke Iwai, Yuri Ooba, Kazutoshi Takahashi, Muneki Isokawa, Sayaka Kawaguchi, Noriko Hatada, Tomohiro Watanabe, Rika Takasugi, Akira Nakayama, Kazutaka Shimbo, Brian. A. Mendelsohn, Tatsuya Okuzumi, Kei Yamada

Version 1 posted 31 January 2023

887

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2

Citations

Biological and Medicinal Chemistry

Bispecific Antibodies Produced via Chemical Site-Specific Conjugation Technology: AJICAP Second Generation

Tomohiro Fujii, Kenichiro Ito, Kazutoshi Takahashi, Tsubasa Aoki, Takuya Seki, Yusuke Iwai, Rika Takasugi, Tomohiro Watanabe, Ryusuke Hirama, Ryo Tsumura, Hirobumi Fuchigami, Masahiro Yasunaga, Yutaka Matsuda

Version 1 posted 25 August 2023

330

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Organic Chemistry

AJICAP-M: Traceless Affinity Peptide Mediated Conjugation Technology for Site-Specific Antibody-Drug Conjugate Synthesis

Yutaka Matsuda, Natsuki Shikida, Noriko Hatada, Kei Yamada, Takuya Seki, Yuichi Nakahara, Yuta Endo, Kazutaka Shimbo, Kazutoshi Takahashi, Akira Nakayama, Brian A. Mendelsohn, Tomohiro Fujii, Tatsuya Okuzumi, Shigeo Hirasawa

Version 1 posted 12 March 2024

622

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1

Citations

Organic Chemistry

Enhanced Chemical Method for Bispecific Antibody Production: Leveraging Site-Specific Conjugation and Stable Crosslinker Technology

Tomohiro Fujii, Yutaka Matsuda

Version 1 posted 20 November 2024

0

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