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    • SATHESH BHAT

    8 results in Authors: SATHESH BHAT

    Category: Biological and Medicinal Chemistry
    ,
    Working Paper
    , Title:

    AutoDesigner, a De Novo Design Algorithm for Rapidly Exploring Large Chemical Space for Lead Optimization: Application to the Design and Synthesis of D-Amino Acid Oxidase Inhibitors

    , Authors: Pieter H Bos, Evelyne M. Houang, Fabio Ranalli, Abba E. Leffler, Nicholas A. Boyles, Volker A. Eyrich, Yuval Luria, Dana Katz, Haifeng Tang, Robert Abel, Sathesh Bhat
    Version 1 posted 20 December 2021
    1,259
    Downloads
    Category: Theoretical and Computational Chemistry
    ,
    Working Paper
    , Title:

    AutoDesigner - Core Design, a De Novo Design Algorithm for Chemical Scaffolds: Application to the Design and Synthesis of Novel Selective Wee1 Inhibitors

    , Authors: Pieter Bos, Fabio Ranalli, Emelie Flood, Shawn Watts, Daigo Inoyama, Jennifer Knight, Anthony Clark, Andrew Placzeck, Jiashi Wang, Aleksey Gerasyuto, Sarah Silvergleid, Wu Yin, Shaoxian Sun, Robert Abel, Sathesh Bhat
    Version 2 posted 14 June 2024
    572
    Downloads
    Category: Biological and Medicinal Chemistry
    ,
    Working Paper
    , Title:

    Discovery of a novel class of D-amino acid oxidase (DAO) inhibitors with the Schrödinger computational platform

    , Authors: Haifeng Tang, Kristian Jensen, Evelyne Houang, Fiona McRobb, Sathesh Bhat, Mats Svensson, Art Bochevarov, Markus Dahlgren, Jeff Bell, Tyler Day, Leah Frye, Robert Skene, James Lewis, James Osborne, Jason Tierney, James Gordon, Maria Palomero-Vazquez, Caroline Gallati, Robert Chapman, Daniel Jones, Kim Hirst, Mark Sephton, Alka Chauhan, Andrew Sharpe, Piero Tardia, Elsa Dechaux, Andrea Taylor, Ross Waddell, Andrea Valentine, Holden Janssens, Omar Aziz, Dawn Bloomfield, Sandeep Ladha, Ian Fraser, John Ellard
    Version 1 posted 20 October 2021
    964
    Downloads
    Category: Biological and Medicinal Chemistry
    ,
    Working Paper
    , Title:

    Discovery of a Novel Mutant-Selective Epidermal Growth Factor Receptor Inhibitor Using in silico Enabled Drug Discovery Platform

    , Authors: Hideyuki Igawa, Zef A. Konst, Eric Therrien, Mee Shelley, Heidi Koldsø, Pieter H. Bos, Ana Negri, Andreas Verras, Jiaye Guo, Markus Dahlgren, Adam Levinson, Brendan T. Parr, Suresh E. Kurhade, Prashant Latthe, Rajesha Shetty, Sridhar Santhanakrishnan, Katherine Amberg-Johnson, Alan Futran, Christian Atsriku, Robert Pelletier, Zhijian Liu, Jeffery A. Bell, Sathesh Bhat, Mats Svensson, Aleksey I. Gerasyuto
    Version 2 posted 21 June 2024
    340
    Downloads
    1
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