Search

10 results in Authors: Oleksandr Grygorenko

Organic Chemistry

Working Paper

Filling the gap in LogP and pK_a evaluation for saturated fluorine-containing derivatives with machine learning

Oleksandr Gurbych, Petro Pavliuk, Dmytro Krasnienkov, Oleksandr Liashuk, Kostiantyn Melnykov, Oleksandr Grygorenko

Version 1 posted 23 July 2024

300

Downloads

Biological and Medicinal Chemistry

Working Paper

Identification of Readily Available Pseudo-Natural Products

Axel Pahl, Oleksandr O. Grygorenko, Ivan S. Kondratov, Herbert Waldmann

Version 1 posted 27 March 2024

304

Downloads

Organic Chemistry

Working Paper

Parallel Minisci Reaction of gem-Difluorocycloalkyl Building Blocks

Serhii Holovach, Illia Poroshyn, Kostiantyn Melnykov, Oleksandr Liashuk, Olena Pariiska, Sergey Kolotilov, Oleksandr Rozhenko, Dmytro Volochnyuk, Oleksandr Grygorenko

Version 1 posted 13 February 2024

414

Downloads

Citations

Organic Chemistry

Working Paper

(Diazomethyl)dimethylphosphine Oxide – A Diazoalkane Reagent for [3+2] Cycloadditions

Evgeniy Slobodyanyuk, Ilona Tarasiuk, Taras Pasichnyk, Dmitriy Volochnyuk, Dmytro Sibgatulin, Oleksandr Grygorenko

Version 1 posted 27 November 2023

349

Downloads

Organic Chemistry

Working Paper

SNAr or Sulfonylation? Chemoselective Amination of Halo(het)arene Sulfonyl Halides for Synthetic Applications and Ultralarge Compound Library Design

Vasyl Naumchyk, Vladyslav Andriashvili, Dmytro Radchenko, Dmytro Dudenko, Yurii Moroz, Andrey Tolmachev, Serhii Zhersh, Oleksandr Grygorenko

Version 1 posted 15 November 2023

371

Downloads

Citations

Organic Chemistry

Working Paper

Bridged Bicyclic gamma-Sultams by Intramolecular Flow Photochemical [2+2] Cycloaddition

Yevhen Zaika, Illia Borodin, Heorhii Olekh, Maksym Kovalov, Oleksandr Diachenko, Volodymyr Brovarets, Bohdan Vashchenko, Oleksandr Grygorenko

Version 1 posted 13 September 2024

362

Downloads

Organic Chemistry

Working Paper

Bicyclo[m.n.k]alkane Building Blocks as Promising Benzene and Cycloalkane Isosteres: Multigram Synthesis, Physicochemical and Structural Characterization

Volodymyr Semeno, Vadym Vasylchenko, Ihor Fesun, Liudmyla Ruzhylo, Mykhailo Kipriianov, Kostiantyn Melnykov, Artem Skreminskyi, Rustam Iminov, Bohdan Vashchenko, Oleksandr Grygorenko

Version 1 posted 14 November 2023

589

Downloads

Organic Chemistry

Working Paper

3,3-Difluorooxetane – a Versatile Functional Group for Bioisosteric Replacements in Drug Discovery

Oleksandr Liashuk, Anastasiya Fedinchyk, Kostiantyn Melnykov, Maksym Herasymchuk, Diana Alieksieieva, Dmytro Lesyk, Yulia Bas, Tatiana Keda, Andriy Yatsymyrskiy, Yuliia Holota, Petro Borysko, Volodymyr Yarmolchuk, Oleksandr Grygorenko

Version 1 posted 14 August 2024

1,182

Downloads

Organic Chemistry

Working Paper

Synthesis of Enantioenriched 2-((Hetera)cyclo)alkylchromanols and their Spirocyclic Analogs through Enzymatic Resolution

Oleksii Timokhin, Anastasiia Romanova, Viktoria Moskvina, Olexandr Kucher, Aleksandr Boiko, Anna Banasevych, Dmytro Durylin, Volodymyr Brovarets, Oleksandr Grygorenko

Version 1 posted 07 November 2024

154

Downloads

Organic Chemistry

Working Paper

Oxetane as a part of modern medicinal chemistry toolbox: the case of 3,3-disubstituted building blocks

Eduard Litskan, Oleksandr Semenchenko, Serhii Lynnyk, Dmitry Granat, Bohdan Vashchenko, Anastasiia Hoida, Daria Tolmachova, Dmytro Leha, Oleksandr Grygorenko, Dmytro Volochnyuk, Serhiy Ryabukhin

Version 1 posted 12 November 2024

894

Downloads

Search

Refine Search

10 results in Oleksandr Grygorenko in Authors: Oleksandr Grygorenko

Filling the gap in LogP and pK_a evaluation for saturated fluorine-containing derivatives with machine learning

Identification of Readily Available Pseudo-Natural Products

Parallel Minisci Reaction of gem-Difluorocycloalkyl Building Blocks

(Diazomethyl)dimethylphosphine Oxide – A Diazoalkane Reagent for [3+2] Cycloadditions

SNAr or Sulfonylation? Chemoselective Amination of Halo(het)arene Sulfonyl Halides for Synthetic Applications and Ultralarge Compound Library Design

Bridged Bicyclic gamma-Sultams by Intramolecular Flow Photochemical [2+2] Cycloaddition

Bicyclo[m.n.k]alkane Building Blocks as Promising Benzene and Cycloalkane Isosteres: Multigram Synthesis, Physicochemical and Structural Characterization

3,3-Difluorooxetane – a Versatile Functional Group for Bioisosteric Replacements in Drug Discovery

Synthesis of Enantioenriched 2-((Hetera)cyclo)alkylchromanols and their Spirocyclic Analogs through Enzymatic Resolution

Oxetane as a part of modern medicinal chemistry toolbox: the case of 3,3-disubstituted building blocks

10 results in Authors: Oleksandr Grygorenko