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12 results in Authors: Martin Fascione

The retaining Pse5Ac7Ac pseudaminyltransferase KpsS1 defines a new glycosyltransferase family (GTXXX)

Abigail Walklett, Emily Flack, Harriet Chidwick, Natasha Hatton, Tessa Keenan, Darshita Budhadev, Julia Walton, Gavin Thomas, Martin Fascione

Version 1 posted 04 December 2023

176

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Organic Chemistry

Working Paper

Catalyst-free site-selective cross-aldol bioconjugations

Nicholas D. Yates, Saeed Akkad, Amanda Noble, Tessa Keenan, Natasha E. Hatton, Nathalie Signoret, Martin Fascione

Version 1 posted 16 June 2022

279

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Biological and Medicinal Chemistry

Working Paper

Site-Selective C-C Modification of Proteins at Neutral pH Using Organocatalyst-Mediated Cross Aldol Ligations

Martin A. Fascione, Richard J. Spears, Robin L. Brabham, Darshita Budhadev, Tessa Keenan, Sophie McKenna, Julia Walton, James. A. Brannigan, A. Marek Brzozowski, Anthony J. Wilkinson, Michael Plevin

Version 1 posted 09 February 2018

745

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Biological and Medicinal Chemistry

Working Paper

Selectivity and stability of N-terminal targeting protein modification chemistries

Lydia Barber, Nicholas Yates, Martin Fascione, Alison Parkin, Glyn Hemsworth, Paul Genever, Christopher Spicer

Version 1 posted 23 August 2022

386

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Biological and Medicinal Chemistry

Working Paper

Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-Fluorinated Monosaccharides

Tessa Keenan, Fabio Parmeggiani, Julien Malassis, Clement Fontenelle, Jean-Baptiste Vendeville, Wendy Offen, Peter Both, kun huang, Andrea Marchesi, Alex Heyam, Carl Young, Simon J. Charnock, Gideon J. Davies, Bruno Linclau, Sabine Flitsch, Martin Fascione

Version 1 posted 09 March 2020

554

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Biological and Medicinal Chemistry

Working Paper

Preparation and Application of an Inexpensive α-Formylglycine Building Block Compatible with Fmoc Solid-Phase Peptide Synthesis

Nicholas Yates, Matthew Warnes, Reuben Breetveld, Christopher Spicer, Nathalie Signoret, Martin Fascione

Version 1 posted 30 November 2022

226

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Citations

Organic Chemistry

Working Paper

A ‘glyco-fluorine’ code revealing differential recognition by glycan binding partners

Kristian Hollingsworth, Antonio Di Maio, Sarah-Jane Richards, Jean-Baptiste Vendeville, David E. Wheatley, Claire E. Council, Tessa Keenan, Helene Ledru, Harriet Chidwick, Huang Kun, Fabio Parmeggiani, Andrea Marchesi, Wengang Chai, Ryan McBerney, Tomasz P. Kaminski, Matthew R. Balmforth, Alexandra Tamasanu, Simon Charnock, Stuart L. Warriner, Michael E. Webb, Martin A. Fascione, Sabine Flitsch, M. Carmen Galan, Ten Feizi, Matthew I. Gibson, Yan Liu, W. Bruce Turnbull, Bruno Linclau

Version 1 posted 10 July 2023

631

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Biological and Medicinal Chemistry

Working Paper

Site-selective protein modification via peptide-directed proximity catalysis

Laetitia Raynal, Joe Nabarro, Lisa Miller, Adam Dowle, Sophie Moul, Steven Johnson, Martin Fascione, Christopher Spicer

Version 1 posted 02 July 2024

342

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Biological and Medicinal Chemistry

Working Paper

3’-O-β-Glycosylation of nucleoside analogues using a promiscuous bacterial glycosyltransferase

Jonathan Dolan, Tessa Keenan, Caecilie Benckendorff, Aisling Ní Cheallaigh, Martin Fascione, Gavin Miller

Version 1 posted 16 May 2024

210

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Biological and Medicinal Chemistry

Working Paper

A Tale of Two Bioconjugations: pH Controlled Divergent Reactivity of Protein A-Oxo Aldehydes in Competing A-Oxo-Mannich and Catalyst-Free Aldol Ligations

Tessa Keenan, Richard Spears, Saeed Akkad, Clare Mahon, Natasha E. Hatton, Julia Walton, Amanda Noble, Nick Yates, Christoph G. Baumann, Alison Parkin, Nathalie Signoret, Martin Fascione

Version 1 posted 07 June 2021

305

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12 results in Martin Fascione in Authors: Martin Fascione

The retaining Pse5Ac7Ac pseudaminyltransferase KpsS1 defines a new glycosyltransferase family (GTXXX)

Catalyst-free site-selective cross-aldol bioconjugations

Site-Selective C-C Modification of Proteins at Neutral pH Using Organocatalyst-Mediated Cross Aldol Ligations

Selectivity and stability of N-terminal targeting protein modification chemistries

Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-Fluorinated Monosaccharides

Preparation and Application of an Inexpensive α-Formylglycine Building Block Compatible with Fmoc Solid-Phase Peptide Synthesis

A ‘glyco-fluorine’ code revealing differential recognition by glycan binding partners

Site-selective protein modification via peptide-directed proximity catalysis

3’-O-β-Glycosylation of nucleoside analogues using a promiscuous bacterial glycosyltransferase

A Tale of Two Bioconjugations: pH Controlled Divergent Reactivity of Protein A-Oxo Aldehydes in Competing A-Oxo-Mannich and Catalyst-Free Aldol Ligations

12 results in Authors: Martin Fascione