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7 results in Authors: Kenneth Durbin

Enhanced payload localization in antibody-drug conjugates using a middle-down mass spectrometry approach with proton transfer charge reduction

Linda Lieu, Cynthia Nagy, Jingjing Huang, Christopher Mullen, Graeme McAlister, Vlad Zabrouskov, Kristina Srzentić, Kenneth Durbin, Rafael Melani, Luca Fornelli

Version 1 posted 27 June 2024

221

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Analytical Chemistry

Working Paper

Targeted Quantification of Proteoforms in Complex Samples by Proteoform Reaction Monitoring

Che-Fan Huang, Jake Kline, Fernanda Negrão, Matthew Robey, Timothy Toby, Kenneth Durbin, Ryan Fellers, John Friedewald, Josh Levitsky, Michael Abecassis, Rafael Melani, Neil Kelleher, Luca Fornelli

Version 1 posted 27 June 2023

389

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Analytical Chemistry

Working Paper

Top-down mass spectrometry analysis of capsid proteins of recombinant adeno-associated virus using multiple ion activations and proton transfer charge reduction

Jake Kline, Jingjing Huang, Linda Lieu, Kristina Srzentić, David Bergen, Christopher Mullen, Graeme McAlister, Kenneth Durbin, Rafael Melani, Luca Fornelli

Version 1 posted 27 June 2024

192

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Analytical Chemistry

Working Paper

Towards a universal method for middle-down analysis of antibodies via proton transfer charge reduction – Orbitrap mass spectrometry

Ryan Oates, Linda Lieu, Jake Kline, Christopher Mullen, Kristina Srzentić, Romain Huguet, Graeme McAlister, Jingjing Huang, David Bergen, Rafael Melani, Vlad Zabrouskov, Kenneth Durbin, John Syka, Luca Fornelli

Version 1 posted 27 June 2024

244

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Analytical Chemistry

Working Paper

Improved label-free quantification of intact proteoforms using field asymmetric ion mobility spectrometry

Jake T. Kline, Michael W. Belford, Jingjing Huang, Joseph B. Greer, David Bergen, Ryan T. Fellers, Sylvester M. Greer, David M. Horn, Vlad Zabrouskov, Romain Huguet, Cornelia L. Boeser, Kenneth R. Durbin, Luca Fornelli

Version 1 posted 05 April 2023

233

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Analytical Chemistry

Working Paper

Orbitrap mass spectrometry and high-field asymmetric waveform ion mobility spectrometry (FAIMS) enable the in-depth analysis of human serum proteoforms

Jake Kline, Michael Belford, Cornelia Boeser, Romain Huguet, Ryan Fellers, Joseph Greer, Sylvester Greer, David Horn, Kenneth Durbin, Jean-Jacques Dunyach, Nagib Ahsan, Luca Fornelli

Version 1 posted 20 February 2023

447

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Analytical Chemistry

Working Paper

Sequential Ion-Ion Reactions for Enhanced Gas-Phase Sequencing of Large Intact Proteins in a Tribrid Orbitrap Mass Spectrometer

Jake Kline, Christopher Mullen, Kenneth Durbin, Ryan Oates, Romain Huguet, John Syka, Luca Fornelli

Version 1 posted 17 February 2021

532

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7 results in Kenneth Durbin in Authors: Kenneth Durbin

Enhanced payload localization in antibody-drug conjugates using a middle-down mass spectrometry approach with proton transfer charge reduction

Targeted Quantification of Proteoforms in Complex Samples by Proteoform Reaction Monitoring

Top-down mass spectrometry analysis of capsid proteins of recombinant adeno-associated virus using multiple ion activations and proton transfer charge reduction

Towards a universal method for middle-down analysis of antibodies via proton transfer charge reduction – Orbitrap mass spectrometry

Improved label-free quantification of intact proteoforms using field asymmetric ion mobility spectrometry

Orbitrap mass spectrometry and high-field asymmetric waveform ion mobility spectrometry (FAIMS) enable the in-depth analysis of human serum proteoforms

Sequential Ion-Ion Reactions for Enhanced Gas-Phase Sequencing of Large Intact Proteins in a Tribrid Orbitrap Mass Spectrometer

7 results in Authors: Kenneth Durbin