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Engineering P450 TamI as an Iterative Biocatalyst for Selective Late-Stage C-H Functionalization and Epoxidation of Tirandamycin Antibiotics

Rosa V. Espinoza, Kersti Caddell Haatveit, S. Wald Grossman, Jin Yi Tan, Caylie A. McGlade, Yogan Khatri, Sean A. Newmister, Jennifer J. Schmidt, Marc Garcia-Borràs, John Montgomery, Kendall N Houk, David H. Sherman

Version 1 posted 16 March 2021

527

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Organic Chemistry

Working Paper

Boosting Chemiexcitation of Phenoxy-1,2-Dioxetanes through 7-Norbornyl and Homocubanyl Spirofusion

Sara Gutkin, Omri Shelef, Zuzana Babjaková, Laura Anna Tomanová, Matej Babjak, Urs Spitz, Qingyang Zhou, Pengchen Ma, Kendall N. Houk, Doron Shabat

Version 1 posted 07 June 2024

366

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Organic Chemistry

Working Paper

Differentiation and Functionalization of Adjacent, Remote C–H Bonds

Hang Shi, Lu Yi, Jiang Weng, Katherine Bay, Xiangyang Chen, Keita Tanaka, pritha verma, Kendall N. Houk, jin-quan yu

Version 1 posted 21 May 2019

854

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Theoretical and Computational Chemistry

Working Paper

autoDIAS: A Python Tool for an Automated Distortion/Interaction Activation Strain Analysis

Dennis Svatunek, Kendall N. Houk

Version 2 posted 21 May 2019

1,810

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Organometallic Chemistry

Working Paper

Demystifying the Soai Reaction

Soumitra Athavale, Adam Simon, Kendall N. Houk, Scott Denmark

Version 1 posted 23 July 2019

1,335

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1

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Catalysis

Working Paper

Selective Enzymatic Oxidation of Silanes to Silanols

Susanne Bähr, Sabine Brinkmann-Chen, Marc Garcia-Borràs, John M Roberts, Dimitris E. Katsoulis, Kendall N Houk, Frances H. Arnold

Version 1 posted 18 March 2020

805

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1

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Inorganic Chemistry

Working Paper

Isolation and X-ray Crystal Structure of an Electrogenerated TEMPO–N3 Charge-Transfer Complex

Hosea Nelson, Juno Siu, Ambarniel Saha, Duilio Cascio, Song-Bai Wu, Chenxi Lu, Jose A. Rodriguez, Kendall N Houk, Song Lin

Version 2 posted 16 April 2020

975

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1

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Biological and Medicinal Chemistry

Working Paper

Molecular Basis of Iterative C–H Oxidation by TamI, a Multifunctional P450 Monooxygenase from the Tirandamycin Biosynthetic Pathway

Sean A. Newmister, Kinshuk Raj Srivastava, Rosa V. Espinoza, Kersti Caddell Haatveit, Yogan Khatri, Rachel M. Martini, Marc Garcia-Borràs, Larissa M. Podust, Kendall N Houk, David H. Sherman

Version 1 posted 27 July 2020

495

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Organic Chemistry

Working Paper

Ligand-Controlled Regiodivergent Palladium-Catalyzed Hydrogermylation of Ynamides

Vincent Debrauwer, Aneta Turlik, Lénaïc Rummler, Alessandro Prescimone, Nicolas Blanchard, Kendall N Houk, Vincent Bizet

Version 1 posted 03 April 2020

639

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Organic Chemistry

Working Paper

Synthesis and Mechanistic Interrogation of Ginkgo biloba Chemical Space en route to (–)-Bilobalide

Robert Demoret, Meghan Baker, Masaki Ohtawa, Shuming Chen, Ching-Ching Lam, Stefano Forli, Kendall N Houk, Ryan Shenvi

Version 2 posted 21 April 2020

2,795

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2

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18 results in Kendall N Houk in Authors: Kendall N Houk

Engineering P450 TamI as an Iterative Biocatalyst for Selective Late-Stage C-H Functionalization and Epoxidation of Tirandamycin Antibiotics

Boosting Chemiexcitation of Phenoxy-1,2-Dioxetanes through 7-Norbornyl and Homocubanyl Spirofusion

Differentiation and Functionalization of Adjacent, Remote C–H Bonds

autoDIAS: A Python Tool for an Automated Distortion/Interaction Activation Strain Analysis

Demystifying the Soai Reaction

Selective Enzymatic Oxidation of Silanes to Silanols

Isolation and X-ray Crystal Structure of an Electrogenerated TEMPO–N3 Charge-Transfer Complex

Molecular Basis of Iterative C–H Oxidation by TamI, a Multifunctional P450 Monooxygenase from the Tirandamycin Biosynthetic Pathway

Ligand-Controlled Regiodivergent Palladium-Catalyzed Hydrogermylation of Ynamides

Synthesis and Mechanistic Interrogation of Ginkgo biloba Chemical Space en route to (–)-Bilobalide

18 results in Authors: Kendall N Houk