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Semisynthetic Analogs of the Antibiotic Fidaxomicin – Design, Synthesis, and Biological Evaluation

Andrea Dorst, Regina Berg, Christoph Gertzen, Daniel Schäfle, katja zerbe, myriam gwerder, Simon Schnell, Peter Sander, Holger Gohlke, Karl Gademann

Version 1 posted 07 July 2020

339

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1

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Organic Chemistry

Working Paper

3-Bromotetrazine: A Versatile Precursor for the Synthesis of 3-Monosubstituted s-Tetrazines and the Labelling of Macromolecules

Simon Schnell, Lukas Hoff, Advaita Panchagnula, Simon Sieber, Anthony Linden, Karl Gademann

Version 1 posted 28 November 2019

927

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Biological and Medicinal Chemistry

Working Paper

Novel Fidaxomicin Antibiotics through Site-Selective Catalysis

David Dailler, Andrea Dorst, Daniel Schäfle, Peter Sander, Karl Gademann

Version 1 posted 02 July 2020

579

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1

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Organic Chemistry

Working Paper

Cross-coupling Reactions of Monosubstituted Tetrazines

Lukas Hoff, Simon Schnell, Andrea Tomio, Anthony Linden, Karl Gademann

Version 1 posted 12 May 2021

375

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Biological and Medicinal Chemistry

Working Paper

Synthesis and Biological Evaluation of Iodinated Fidaxomicin Antibiotics

Andrea Dorst, Inga S. Shchelik, Daniel Schäfle, Peter Sander, Karl Gademann

Version 2 posted 21 July 2020

513

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Organic Chemistry

Working Paper

Design, Synthesis, and Biological Evaluation of Light-Activated Antibiotics

Inga S. Shchelik, Andrea Tomio, Karl Gademann

Version 1 posted 12 January 2021

807

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Biological and Medicinal Chemistry

Working Paper

A Volatile Signal Controls Virulence in the Plant Pathogen Pseudomonas syringae pv. syringae and a Strategy for Infection Control in Organic Farming

Simon Sieber, Anugraha Mathew, Christian Jenul, Tobias Kohler, Max Bär, Victor J. Carrion, Francisco M. Cazorla, Urs Stalder, Ya-Chu Hsieh, Laurent Bigler, Leo Eberl, Karl Gademann

Version 1 posted 03 September 2020

390

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1

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Organic Chemistry

Working Paper

Nucleophilic Attack on Nitrogen in Tetrazines by Silyl-Enol Ethers

Simon Schnell, Mauro Schilling, Jan Sklyaruk, Anthony Linden, Sandra Luber, Karl Gademann

Version 1 posted 20 October 2020

715

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1

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Catalysis

Working Paper

Cross-Coupling Reactions of 5-Bromo-1,2,3-triazines

Lukas Hoff, Joana Hauser, Karl Gademann

Version 1 posted 15 July 2022

654

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1

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Biological and Medicinal Chemistry

Working Paper

Phenolic Substitution in Fidaxomicin: A Semisynthetic Approach to Antibiotic Activity Across Species

Erik Jung, Anastassia Kraimps, Silvia Dittmann, Tizian Griesser, Jordan Costafrolaz, Yves Mattenberger, Simon Jurt, Patrick H. Viollier, Peter Sander, Susanne Sievers, Karl Gademann

Version 1 posted 16 August 2023

128

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12 results in Karl Gademann in Authors: Karl Gademann

Semisynthetic Analogs of the Antibiotic Fidaxomicin – Design, Synthesis, and Biological Evaluation

3-Bromotetrazine: A Versatile Precursor for the Synthesis of 3-Monosubstituted s-Tetrazines and the Labelling of Macromolecules

Novel Fidaxomicin Antibiotics through Site-Selective Catalysis

Cross-coupling Reactions of Monosubstituted Tetrazines

Synthesis and Biological Evaluation of Iodinated Fidaxomicin Antibiotics

Design, Synthesis, and Biological Evaluation of Light-Activated Antibiotics

A Volatile Signal Controls Virulence in the Plant Pathogen Pseudomonas syringae pv. syringae and a Strategy for Infection Control in Organic Farming

Nucleophilic Attack on Nitrogen in Tetrazines by Silyl-Enol Ethers

Cross-Coupling Reactions of 5-Bromo-1,2,3-triazines

Phenolic Substitution in Fidaxomicin: A Semisynthetic Approach to Antibiotic Activity Across Species

12 results in Authors: Karl Gademann