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Fungal Indole Alkaloid Biogenesis Through Evolution of a Bifunctional Reductase/Diels-Alderase

Qingyun Dan, Sean A. Newmister, Kimberly R. Klas, Amy E. Fraley, Timothy J. McAfoos, Amber D. Somoza, James D. Sunderhaus, Ying Ye, Vikram V. Shende, Fengan Yu, Jacob N. Sanders, W. Clay Brown, Le Zhao, Robert S. Paton, K. N. Houk, Janet L. Smith, David H. Sherman, Robert M. Williams

Version 1 posted 26 December 2018

1,250

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Catalysis

Working Paper

A Biocatalytic Platform for Synthesis of Chiral α-Trifluoromethylated Organoborons

Xiongyi Huang, Marc Garcia-Borràs, Kun Miao, S. B. Jennifer Kan, Arjun Zutshi, K. N. Houk, Frances H. Arnold

Version 1 posted 26 September 2018

1,404

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Catalysis

Working Paper

Unified Template Strategy for Editing Multiple Remote C–H Bonds

Zhoulong Fan, Xiangyang Chen, Keita Tanaka, Han Seul Park, Nelson Y. S. Lam, Jonathan J. Wong, K. N. Houk, Jin-Quan Yu

Version 1 posted 11 October 2021

1,001

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Theoretical and Computational Chemistry

Working Paper

Energizing Listless Pyrimidines by Pre-Distortion for the General Synthesis of 7-Aza-Indazoles from 2-Hydrazonylpyrimidines via Intramolecular Diels-Alder Reactions

Vincent Le Fouler, yu Chen, Vincent Gandon, Vincent Bizet, Christophe Salomé, Thomas Fessard, Fang Liu, K. N. Houk, Nicolas Blanchard

Version 1 posted 06 June 2019

735

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Catalysis

Working Paper

Analysis of Laboratory-Evolved Flavin-Dependent Halogenases Affords a Computational Model for Predicting Halogenase Site Selectivity

Mary C. Andorfer, Declan Evans, Song Yang, Cyndi Q. He, Anna M. Girlich, Jaylie Vergara-Coll, Narayanasami Sukumar, K. N. Houk, Jared C. Lewis

Version 1 posted 16 February 2022

422

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Organic Chemistry

Working Paper

Modular synthesis of 1,2-azaborines via ring-opening BN-isostere benzannulation

Hairong LYU, Thomas H. Tugwell, Zhijie Chen, Garrett A. Kukier, Aneta Turlik, Yifei Wu, K. N. Houk, Peng Liu, Guangbin Dong

Version 1 posted 21 March 2023

1,934

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Organic Chemistry

Working Paper

Organocatalytic Discrimination of Non-Directing Aryl and Heteroaryl Groups: Enantioselective Synthesis of Bioactive Indole-Containing Triarylmethanes

Qiaolin Yan, Meng Duan, Cien Chen, Zhiqin Deng, Mandi Wu, Peiyuan Yu, Ming-liang He, Guangyu Zhu, K. N. Houk, Jianwei Sun

Version 2 posted 03 December 2021

551

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Organic Chemistry

Working Paper

Bioinspired Asymmetric Total Synthesis of Emeriones A–C

Sven Jänner, Daniel Isak, Yuli Li, K. N. Houk, Aubry Miller

Version 2 posted 22 April 2022

1,148

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Inorganic Chemistry

Working Paper

Arene C–H Borylation Strategy Enabled by a Non-Classical Boron Cluster-Based Electrophile

Sangmin Kim, Joseph Treacy, Jordan Gonzalez, Milan Gembicky, K. N. Houk, Alexander Spokoyny

Version 1 posted 18 July 2022

665

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Organic Chemistry

Working Paper

High-pressure reaction profiles and activation volumes of 1,3-cyclohexadiene dimerizations computed by the extreme pressure-polarizable continuum model (XP-PCM)

Bo Chen, K. N. Houk, Roberto Cammi

Version 1 posted 28 September 2021

298

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12 results in K. N. Houk in Authors: K. N. Houk

Fungal Indole Alkaloid Biogenesis Through Evolution of a Bifunctional Reductase/Diels-Alderase

A Biocatalytic Platform for Synthesis of Chiral α-Trifluoromethylated Organoborons

Unified Template Strategy for Editing Multiple Remote C–H Bonds

Energizing Listless Pyrimidines by Pre-Distortion for the General Synthesis of 7-Aza-Indazoles from 2-Hydrazonylpyrimidines via Intramolecular Diels-Alder Reactions

Analysis of Laboratory-Evolved Flavin-Dependent Halogenases Affords a Computational Model for Predicting Halogenase Site Selectivity

Modular synthesis of 1,2-azaborines via ring-opening BN-isostere benzannulation

Organocatalytic Discrimination of Non-Directing Aryl and Heteroaryl Groups: Enantioselective Synthesis of Bioactive Indole-Containing Triarylmethanes

Bioinspired Asymmetric Total Synthesis of Emeriones A–C

Arene C–H Borylation Strategy Enabled by a Non-Classical Boron Cluster-Based Electrophile

High-pressure reaction profiles and activation volumes of 1,3-cyclohexadiene dimerizations computed by the extreme pressure-polarizable continuum model (XP-PCM)

12 results in Authors: K. N. Houk