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Organic Chemistry

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Ascorbate Peroxidase (APEX2) Activates Dihydrotetrazine Oxidation for Rapid Bioorthogonal Chemistry in Living Cells

Sophia Neglia, Amanda Tallon, Christopher am Ende, Colin Thorpe, Joseph Fox

Version 1 posted 18 March 2025

198

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Organic Chemistry

Working Paper

General, Divergent Platform for Diastereoselective Synthesis of trans-Cyclooctenes with High Reactivity and Favorable Physiochemical Properties

Jessica E. Pigga, Julia Rosenberger, Andrew Jemas, Samantha Boyd, Olga Dmitrenko, Yixin Xie, Joseph Fox

Version 1 posted 03 February 2021

539

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Organic Chemistry

Working Paper

Divergent Synthesis of Monosubstituted and Unsymmetrical 3,6- Disubstituted Tetrazines from Carboxylic Ester Precursors

Yixin Xie, Yinzhi Fang, Zhen Huang, Amanda Tallon, Christopher W. am Ende, Joseph Fox

Version 1 posted 29 April 2020

757

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Catalysis

Working Paper

Enabling in vivo Photocatalytic Activation of Rapid Bioorthogonal Chemistry by Repurposing Si-Rhodamine Fluorophores as Cytocompatible Far-Red Photocatalysts

Chuanqi Wang, He Zhang, Tao Zhang, Xiaoyu Zou, Hui Wang, Julia Rosenberger, Raghu Vannam, William Trout, Xinqiao Jia, Zibo Li, Joseph Fox

Version 1 posted 04 January 2021

630

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Organic Chemistry

Working Paper

Thiomethyltetrazines are Reversible Covalent Cysteine Warheads whose Dynamic Behavior can be "Switched off” via Bioorthogonal Chemistry Inside Live Cells

Amanda Tallon, Yingrong Xu, Graham West, Christopher am Ende, Joseph Fox

Version 1 posted 02 May 2023

1,088

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Biological and Medicinal Chemistry

Working Paper

Catalytic Activation of Bioorthogonal Chemistry with Light (CABL) Enables Rapid, Spatiotemporally-controlled Labeling and No-Wash, Subcellular 3D-Patterning in Live Cells using Long Wavelength Light

Andrew Jemas, Yixin Xie, Jessica Pigga, Jeffrey Caplan, Christopher am Ende, Joseph Fox

Version 1 posted 01 October 2021

1,169

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Organic Chemistry

Working Paper

Affinity Bioorthogonal Chemistry (ABC) Tags for Site-selective Conjugation, On-resin Protein-Protein Coupling, and Purification of Protein Conjugates

Joseph Fox, Samuel Scinto, Tyler Reagle

Version 1 posted 31 May 2022

670

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Biological and Medicinal Chemistry

Working Paper

Ligand-directed Photocatalysts and Far-red Light Enable Catalytic Bioorthogonal Uncaging inside Live Cells

Julia Rosenberger, Yixin Xie, Yinzhi Fang, Xinyi Lyu, William Trout, Olga Dmitrenko, Joseph Fox

Version 2 posted 07 October 2022

962

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Materials Science

Working Paper

Bioorthogonal Polymerization of Coiled-Coil Peptides

Hanyuan Gao, Tianren Zhang, Matthew Langenstein, Weiran Xie, Samiksha Udan, Zihan Zhang, Jeffery Saven, Shi Bai, Darrin Pochan, Joseph Fox, Xinqiao Jia

Version 1 posted 10 May 2024

505

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Organic Chemistry

Working Paper

Mechanistic Differences between Linear vs Spirocyclic Dialkyldiazirine Probes for Photoaffinity Labeling

Jessica O'Brien, Louis Conway, Paramesh Ramaraj, Appaso Jadhav, Jun Jin, Jason Dutra, Parrish Evers, Shadi Masoud, Manuel Schupp, Iakovos Saridakis, Yong Chen, Nuno Maulide, John Pezacki, Christopher am Ende, Christopher Parker, Joseph Fox

Version 1 posted 22 July 2024

312

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10 results in Joseph Fox in Authors: Joseph Fox

Ascorbate Peroxidase (APEX2) Activates Dihydrotetrazine Oxidation for Rapid Bioorthogonal Chemistry in Living Cells

General, Divergent Platform for Diastereoselective Synthesis of trans-Cyclooctenes with High Reactivity and Favorable Physiochemical Properties

Divergent Synthesis of Monosubstituted and Unsymmetrical 3,6- Disubstituted Tetrazines from Carboxylic Ester Precursors

Enabling in vivo Photocatalytic Activation of Rapid Bioorthogonal Chemistry by Repurposing Si-Rhodamine Fluorophores as Cytocompatible Far-Red Photocatalysts

Thiomethyltetrazines are Reversible Covalent Cysteine Warheads whose Dynamic Behavior can be "Switched off” via Bioorthogonal Chemistry Inside Live Cells

Catalytic Activation of Bioorthogonal Chemistry with Light (CABL) Enables Rapid, Spatiotemporally-controlled Labeling and No-Wash, Subcellular 3D-Patterning in Live Cells using Long Wavelength Light

Affinity Bioorthogonal Chemistry (ABC) Tags for Site-selective Conjugation, On-resin Protein-Protein Coupling, and Purification of Protein Conjugates

Ligand-directed Photocatalysts and Far-red Light Enable Catalytic Bioorthogonal Uncaging inside Live Cells

Bioorthogonal Polymerization of Coiled-Coil Peptides

Mechanistic Differences between Linear vs Spirocyclic Dialkyldiazirine Probes for Photoaffinity Labeling

10 results in Authors: Joseph Fox