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Catalysis

Working Paper

A Biocatalytic Platform for Synthesis of Chiral α-Trifluoromethylated Organoborons

Xiongyi Huang, Marc Garcia-Borràs, Kun Miao, S. B. Jennifer Kan, Arjun Zutshi, K. N. Houk, Frances H. Arnold

Version 1 posted 26 September 2018

1,421

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Catalysis

Working Paper

Chemodivergent C(sp3)–H and C(sp2)–H Cyanomethylation Using Engineered Carbene Transferases

Juner Zhang, Ailiena Maggiolo, Edwin Alfonzo, Runze Mao, Nicholas Porter, Nayla Abney, Frances Arnold

Version 1 posted 12 October 2022

727

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Catalysis

Working Paper

Biocatalytic, Enantioenriched Primary Amination of Tertiary C–H Bonds

Runze Mao, Shilong Gao, Zi-Yang Qin, Torben Rogge, Sophia Wu, Zi-Qi Li, Anuvab Das, Kendall Houk, Frances Arnold

Version 1 posted 13 December 2023

1,476

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1

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Catalysis

Working Paper

Directed Evolution Enables Dynamic Control of Transient Intermediates for Anti-Markovnikov Wacker-Tsuji-Type Oxidation of Unactivated Alkenes

Cindy Klaus, Jordi Soler, Grzegorz Kubik, Yosephine Gumulya, Yue Hui, Ella J. Watkins-Dulaney, Max-Luca Heitland, Marc Sommer, Alina Klein, Julia L. Kowal, Hartmut H. Niemann, Frances H. Arnold, Marc Garcia-Borràs, Stephan C. Hammer

Version 2 posted 17 September 2024

694

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Biological and Medicinal Chemistry

Working Paper

Engineered Biosynthesis of β-Alkyl Tryptophan Analogs

Christina E. Boville, Remkes A. Scheele, Philipp Koch, Sabine Brinkmann-Chen, Andrew R. Buller, Frances H. Arnold

Version 1 posted 13 July 2018

738

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Catalysis

Working Paper

Reversing the enantioselectivity of enzymatic carbene N–H insertion through mechanism-guided protein engineering

Carla Calvó-Tusell, Zhen Liu, Kai Chen, Frances H. Arnold, Marc Garcia-Borràs

Version 1 posted 18 August 2022

617

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3

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Catalysis

Working Paper

Selective Enzymatic Oxidation of Silanes to Silanols

Susanne Bähr, Sabine Brinkmann-Chen, Marc Garcia-Borràs, John M Roberts, Dimitris E. Katsoulis, Kendall N Houk, Frances H. Arnold

Version 1 posted 18 March 2020

732

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1

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Biological and Medicinal Chemistry

Working Paper

Site-selective enzymatic C‒H amidation for synthesis of diverse lactams

Inha Cho, Zhijun Jia, Frances H. Arnold

Version 2 posted 03 January 2020

2,713

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Catalysis

Working Paper

Biocatalytic Carbene Transfer Using Diazirines

Nicholas Porter, Emma Danelius, Tamir Gonen, Frances Arnold

Version 1 posted 04 May 2022

728

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Catalysis

Working Paper

Biocatalytic One-Carbon Ring Expansion of Aziridines to Azetidines via a Highly Enantioselective [1,2]-Stevens Rearrangement

David Miller, Ravi Lal, Luca Marchetti, Frances Arnold

Version 3 posted 17 January 2022

1,666

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16 results in Frances Arnold in Authors: Frances Arnold

A Biocatalytic Platform for Synthesis of Chiral α-Trifluoromethylated Organoborons

Chemodivergent C(sp3)–H and C(sp2)–H Cyanomethylation Using Engineered Carbene Transferases

Biocatalytic, Enantioenriched Primary Amination of Tertiary C–H Bonds

Directed Evolution Enables Dynamic Control of Transient Intermediates for Anti-Markovnikov Wacker-Tsuji-Type Oxidation of Unactivated Alkenes

Engineered Biosynthesis of β-Alkyl Tryptophan Analogs

Reversing the enantioselectivity of enzymatic carbene N–H insertion through mechanism-guided protein engineering

Selective Enzymatic Oxidation of Silanes to Silanols

Site-selective enzymatic C‒H amidation for synthesis of diverse lactams

Biocatalytic Carbene Transfer Using Diazirines

Biocatalytic One-Carbon Ring Expansion of Aziridines to Azetidines via a Highly Enantioselective [1,2]-Stevens Rearrangement

16 results in Authors: Frances Arnold