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Biological and Medicinal Chemistry

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Dominika Ewa Pieńkowska

2 results in Authors: Dominika Ewa Pieńkowska

Biological and Medicinal Chemistry

Development and characterization of the first selective class IIb histone deacetylase degraders

Shiyang Zhai, Irina Honin, Linda Schäker-Hübner, Maria Hanl, Lukas Jacobi, Finn Dressler, Dominika Ewa Pieńkowska, Philipp König, Jan Gerhartz, Rabea Voget, Gerd Bendas, Michael Gütschow, Felix Meissner, Björn Burckhardt, Radosław P. Nowak, Christian Steinebach, Finn Kristian Hansen

Version 3 posted 06 March 2025

736

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Biological and Medicinal Chemistry

Discovery of histone deacetylase 8 (HDAC8)-specific proteolysis-targeting chimeras with anti-cancer activity against hematological malignancies

Shiyang Zhai, Marie Kemkes, Cindy-Esther Kponomaizoun, Felix Feller, Jia-Wey Tu, Dominika Ewa Pieńkowska, Jan Gerhartz, Julian Schliehe-Diecks, Michael Gütschow, Radosław P. Nowak, Christian Steinebach, Sanil Bhatia, Finn Kristian Hansen

Version 1 posted 04 April 2025

152

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