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Mechanism-Based Strategy for Optimizing HaloTag Protein Labeling

Sérgio Marques, Michaela Slanska, Klaudia Chmelova, Radka Chaloupkova, Martin Marek, Spencer Clark, Jiri Damborsky, Eric T. Kool, David Bednar, Zbynek Prokop

Version 1 posted 07 December 2021

803

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Biological and Medicinal Chemistry

Working Paper

SoluProt: Prediction of Soluble Protein Expression in Escherichia coli

Jiri Hon, Martin Marusiak, Tomas Martinek, Antonin Kunka, Jaroslav Zendulka, David Bednar, Jiri Damborsky

Version 1 posted 05 October 2020

612

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1

Citations

Catalysis

Working Paper

Substrate Inhibition by the Blockage of Product Release and Its Control by Tunnel Engineering

Piia Kokkonen, Andy Beier, Stanislav Mazurenko, Jiri Damborsky, David Bednar, Zbynek Prokop

Version 1 posted 02 December 2020

307

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Catalysis

Working Paper

Engineering Protein Dynamics of Ancestral Luciferase

Andrea Schenkmayerova, Gaspar Pinto, Martin Toul, Martin Marek, Lenka Hernychova, Joan Planas-Iglesias, Veronika Liskova, Daniel Pluskal, Michal Vasina, Stephane Emond, Mark Doerr, Radka Chaloupková, David Bednar, Zbynek Prokop, Florian Hollfelder, Uwe T. Bornscheuer, Jiri Damborsky

Version 1 posted 17 August 2020

383

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1

Citations

Catalysis

Working Paper

Computational Protein Stabilization Can Affect Folding Energy Landscapes and Lead to Domain-Swapped Dimers

Klara Markova, Antonin Kunka, Klaudia Chmelova, Martin Havlasek, Petra Babkova, Sérgio M. Marques, Michal Vasina, Joan Planas-Iglesias, Radka Chaloupková, David Bednar, Zbynek Prokop, Jiri Damborsky, Martin Marek

Version 1 posted 27 January 2021

509

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Catalysis

Working Paper

Advanced Database Mining of Efficient Biocatalysts by Sequence and Structure Bioinformatics and Microfluidics

Michal Vasina, Pavel Vanacek, Jiri Hon, David Kovar, Hana Faldynova, Antonin Kunka, Tomas Buryska, Christoffel P. S. Badenhorst, Stanislav Mazurenko, David Bednar, Stavros Stavrakis, Uwe T. Bornscheuer, Andrew de Mello, Jiri Damborsky, Zbynek Prokop

Version 2 posted 12 May 2022

984

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Biological and Medicinal Chemistry

Working Paper

Screening of World Approved Drugs against Highly Dynamical Spike Glycoprotein SARS-CoV-2 using CaverDock and Machine Learning

Gaspar Pinto, Ondrej Vavra, Sérgio M. Marques, Jiri Filipovic, David Bednar, Jiri Damborsky

Version 2 posted 07 December 2020

881

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Catalysis

Working Paper

Engineering Dehalogenase Enzymes using Variational Autoencoder-Generated Latent Spaces and Microfluidics

Pavel Kohout, Michal Vasina, Marika Majerova, Veronika Novakova, Jiri Damborsky, David Bednar, Martin Marek, Zbynek Prokop, Stanislav Mazurenko

Version 2 posted 18 April 2024

776

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Catalysis

Review

Accelerating Enzyme Engineering with Quantum Power: Quest for Quantum Advantage in Biocatalysis

Jiri Damborsky, Petr Kouba, Josef Sivic, David Bednar, Stanislav Mazurenko

Version 1 posted 19 November 2024

9

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9 results in David Bednar in Authors: David Bednar

Mechanism-Based Strategy for Optimizing HaloTag Protein Labeling

SoluProt: Prediction of Soluble Protein Expression in Escherichia coli

Substrate Inhibition by the Blockage of Product Release and Its Control by Tunnel Engineering

Engineering Protein Dynamics of Ancestral Luciferase

Computational Protein Stabilization Can Affect Folding Energy Landscapes and Lead to Domain-Swapped Dimers

Advanced Database Mining of Efficient Biocatalysts by Sequence and Structure Bioinformatics and Microfluidics

Screening of World Approved Drugs against Highly Dynamical Spike Glycoprotein SARS-CoV-2 using CaverDock and Machine Learning

Engineering Dehalogenase Enzymes using Variational Autoencoder-Generated Latent Spaces and Microfluidics

Accelerating Enzyme Engineering with Quantum Power: Quest for Quantum Advantage in Biocatalysis

9 results in Authors: David Bednar