Advanced Mass Spectrometry Techniques for the Structural Characterisation of Supramolecules and Coordination Compounds

Mass spectrometry is routinely used for myriad applications in clinical, industrial, and research laboratories worldwide. Developments in the areas of ionisation sources, high-resolution mass analysers, tandem mass spectrometry, and ion mobility have significantly extended the repertoire of mass spectrometrists, however for coordination compounds and supramolecules, mass spectrometry remains underexplored and arguably underappreciated. Here, I aim to guide the reader through different tools of modern mass spectrometry that are suitable for larger inorganic complexes. I will discuss all steps, from choosing the right technique(s), over sample preparation and technical details to data analysis and interpretation. The main target audience of this tutorial are synthetic chemists and technicians, as well as mass spectrometrists with little experience in characterising labile inorganic compounds.