Abstract
Spiro[3.3]heptane can mimic the mono-, meta- and para-substituted phenyl rings in drugs.
Supplementary materials
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Supporting Information
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Spiro[3.3]heptane as a Non-collinear Benzene Bioisostere
02 November 2023, Version 2
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.
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Version History
Nov 02, 2023 Version 2
Version Notes
revised version with new biological data
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Funding
European Research Council
101000893
Author’s competing interest statement
Authors of the manuscript are employees of a chemcial supplier Enamine.
Ethics
The author(s) declare that they have sought and gained approval from the
relevant ethics committee/IRB for this research and its publication.