Spiro[3.3]heptane as a Non-collinear Benzene Bioisostere

25 July 2023, Version 1

Abstract

Spiro[3.3]heptane can mimic the mono-, meta- and para-substituted phenyl rings in drugs.

Keywords

spiro[3.3]heptane
bicyclo[1.1.1]pentane
saturation
phenyl
bioisosteres

Supplementary materials

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