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Silyl formates as hydrosilane surrogates for the transfer hydrosilylation of ketones

11 January 2022, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

An energetically and atom economic transfer hydrosilylation of ketones employing silyl formates as hydrosilanes surrogates under mild conditions is presented. A total of 24 examples of ketones have been successfully converted to their corresponding silyl ethers with 61-99% yield in the presence of a PNHP-based ruthenium catalyst and silyl formate reagent. The crucial role of the ligand for the transformation is demonstrated.

Keywords

Silyl formate
surrogate
hydrosilylation
carbonyl reduction
participative ligand

Supplementary materials

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Description
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Supporting information
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Experimental procedures and compilation of spectral and analytical data of all new compounds
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Version History

Jan 11, 2022 Version 1

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The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv-2022-ww7pj
D O I: 10.26434/chemrxiv-2022-ww7pj [opens in a new tab]

Funding

CEA
CNRS
ERC
Consolidator Grant 818260
Labex Charmmmat
ANR-11-LABX-003
Institut de France

Author’s competing interest statement

The author(s) have declared they have no conflict of interest with regard to this content

Ethics

The author(s) have declared ethics committee/IRB approval is not relevant to this content

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