Divergent Synthesis of Complex ent-Kauranes, ent-Atisanes and ent-Trachylobanes via a Hybrid Oxidative Approach

Xiao Zhang; Emma King-Smith; Liao-Bin Dong; Li-Cheng Yang; Jeffrey D. Rudolf; Ben Shen; Hans Renata

doi:10.26434/chemrxiv.7663112.v2

Organic Chemistry

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Divergent Synthesis of Complex ent-Kauranes, ent-Atisanes and ent-Trachylobanes via a Hybrid Oxidative Approach

Working Paper

Xiao Zhang ,
Emma King-Smith ,
Liao-Bin Dong ,
Li-Cheng Yang ,
Jeffrey D. Rudolf ,
Ben Shen ,
Hans Renata The Scripps Research Institute

Abstract

Nine complex diterpenes were synthesized using a hybrid oxidative approach that combines chemical and enzymatic C–H oxidation methods.

Content

Thumbnail image of Kaurane 032020 Chemrxiv.pdf

Supplementary material

Kaurane SI combined 032020

Version History

Mar 23, 2020 Version 2

Feb 04, 2019 Version 1

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6,646

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1,742

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2

License

The content is available under CC BY NC ND 4.0 License CreativeCommons.org

DOI

10.26434/chemrxiv.7663112.v2

Funding

GM128895

GM134954

GM124461

Author’s competing interest statement

The authors declare no conflict of interest

Keywords

biocatalysis

total synthesis

C–H functionalization

terpenes

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This content is an early or alternative research output and has not been peer-reviewed at the time of posting.

Divergent Synthesis of Complex ent-Kauranes, ent-Atisanes and ent-Trachylobanes via a Hybrid Oxidative Approach

Authors

Abstract

Content

Supplementary material

Version History

Metrics

License

DOI

Funding

Author’s competing interest statement

Keywords

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Publication