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Zwitterionic AIEgens: Rational Molecular Design for NIR-II Fluorescence Imaging-Guided Synergistic Phototherapy

preprint
revised on 22.06.2020 and posted on 24.06.2020 by wei zhu, Miaomiao Kang, qian wu, Zhijun Zhang, yi wu, Chunbin Li, Kai LI, Lei Wang, Dong Wang, Ben Zhong Tang
Fluorescence imaging in the second near-infrared region (NIR-II) can penetrate tissue at centimeter depths and obtain high fidelity of images. However, facile synthesis of small-molecule fluorescent photosensitizers for efficient NIR-II fluorescence imaging as well as photodynamic and photothermal combinatorial therapies (PDT-PTT) is still a challenging task. Herein, we reported a rational design and facile synthesis protocol for a series of novel NIR-emissive zwitterionic luminogens with aggregation-induced emission (AIE) features for cancer phototheranostics.

History

Email Address of Submitting Author

willian_fox@163.com

Institution

Shenzhen University

Country

China

ORCID For Submitting Author

0000-0001-7759-2903

Declaration of Conflict of Interest

The authors declare no competing financial interest.

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