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revised on 07.10.2020 and posted on 07.10.2020by Ofir Schuster, Anat Zvi, Osnat Rosen, Hagit Achdout, Amir Ben-Shmuel, Ohad Shifman, Shmuel Yitzhaki, Orly Laskar, Liron Feldberg
This study describes the development of a novel assay for SARS-CoV-2
identification using LC-MS/MS analysis. A multi-step procedure for the rational
down-selection of a set of markers has leaded to the discovery of six
SARS-CoV-2 specific and sensitive markers, enabling the reliable identification
of the virus. A rapid and simple assay was developed, successfully applied to
clinical nasopharyngeal samples. The assay may potentially serve as a
complementary approach for SARS-CoV-2 identification.