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Specific and Rapid SARS-CoV-2 Identification Based on LC-MS/MS Analysis

preprint
revised on 07.10.2020 and posted on 07.10.2020 by Ofir Schuster, Anat Zvi, Osnat Rosen, Hagit Achdout, Amir Ben-Shmuel, Ohad Shifman, Shmuel Yitzhaki, Orly Laskar, Liron Feldberg
This study describes the development of a novel assay for SARS-CoV-2 identification using LC-MS/MS analysis. A multi-step procedure for the rational down-selection of a set of markers has leaded to the discovery of six SARS-CoV-2 specific and sensitive markers, enabling the reliable identification of the virus. A rapid and simple assay was developed, successfully applied to clinical nasopharyngeal samples. The assay may potentially serve as a complementary approach for SARS-CoV-2 identification.

History

Email Address of Submitting Author

ofirsc@iibr.gov.il

Institution

Israel Institute for Biological Research

Country

Israel

ORCID For Submitting Author

0000-0001-6379-9292

Declaration of Conflict of Interest

We declare no conflict of interest

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