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Mechanosynthesis of a Coamorphous Formulation of Creatine with Citric Acid and Humidity–Mediated Transformation into a Cocrystal
preprintsubmitted on 28.09.2020, 03:17 and posted on 29.09.2020, 13:24 by Kyle B Pekar, Jonathan B Lefton, Christina McConville, Jewel Burleson, Daniel Sethio, Elfi Kraka, Tomce Runcevski
We report a simple, efficient, and scalable mechanochemical method of preparation of new creatine fitness supplement with increased solubility (compared to the creatine monohydrate) and decreased acidity (compared to creatine hydrochloride).