ChemRxiv
These are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information. For more information, please see our FAQs.
1/1
0/0

Aniline-Containing Derivatives of Parthenolide: Synthesis and Anti-Chronic Lymphocytic Leukaemia Activity

preprint
revised on 25.06.2020 and posted on 29.06.2020 by Alex Quy, Xingjian Li, Louise Male, Tatjana Stankovic, Angelo Agathanggelou, John Fossey
A protocol for squaric acid-catalysed 1,4-addition of aniline derivatives to parthenolide is identified, developed and disclosed.

Funding

MRC Confidence in Concepts (14/15)

EPSRC (ISF 2012)

ERDF AWM II

University of Birmingham

Royal Society Industrial Fellowship (6955)

EPSRC (EP/J003220/1)

Bloodwise (14031)

History

Email Address of Submitting Author

j.s.fossey@bham.ac.uk

Institution

University of Birmingham

Country

United Kingdom

ORCID For Submitting Author

0000-0002-2626-5117

Declaration of Conflict of Interest

The authors declare no competing financial interests.

Exports