Aniline-Containing Derivatives of Parthenolide: Synthesis and Anti-Chronic Lymphocytic Leukaemia Activity

25 June 2020, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

A protocol for squaric acid-catalysed 1,4-addition of aniline derivatives to parthenolide is identified, developed and disclosed.

Keywords

Parthenolide (PTL)
Chronic lymphocytic leukaemia (CLL)
Chronic lymphocytic leukemia (CLL)
Aniline
1,4-Conjugate addition

Supplementary materials

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01 ESI ALF02 20200623
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