![Author ORCID: We display the ORCID iD icon alongside authors names on our website to acknowledge that the ORCiD has been authenticated when entered by the user. To view the users ORCiD record click the icon. [opens in a new tab]](https://chemrxiv.org/engage/assets/public/chemrxiv/images/logos/orcid.png)
Abstract
A regional outbreak of pneumonia in Wuhan, Hubei Province of China in late 2019 was associated with a novel coronavirus. Rapid release of genomic data for the isolated virus enabled the construction of first-generation homology models of the new CoV 3CLpro cysteine protease. Whilst the overall viral genome was most closely associated with bat coronaviruses, the main protease is most closely related (96% identity) to SARS CoV protease.
Supplementary materials
Title
TOC graphic
Description
Actions
Title
EMBOSS NEEDLE Alignments
Description
Actions
Title
Raw models
Description
Actions
Title
Refined Dimers
Description
Actions
Title
Refined monomers
Description
Actions
Title
Bat WH SARS protease
Description
Actions
Title
README
Description
Actions
Title
WH human 3CLproModel2 from3vb3 Minimised
Description
Actions
Title
Stoermer 2020 Wuhan CoV 3CLpro SI040220
Description
Actions
Title
Stoermer 2020 Wuhan CoV 3CLpro040220
Description
Actions
Title
Stoermer 2020 Wuhan CoV 3CLpro SI040220
Description
Actions
